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该问题已由【乐利来】赵胜解答
1、医院是治“已病”， 生殖美疗防“未病”。中医治未病理念：“未病先防，已病防变” 吴仪强调：“中医学中有一个理念：上工治未病。我理解就是重视预防和保jian，也就是防患于未然。如果预防工作做得好，身体健壮，抵抗力增强了，不生病或少生病不是更好吗？” 2、自然疗法：物理zhi liao，不含激素，不含化学成份，无毒副作用； 3、效率极高：直达病灶、弥散无死角，强力杀菌、快捷修复； 4、自美效果：面部枯黄、晦暗、发青发灰、出现色斑、皮肤干枯多皱，75％的女性是由各种妇科病所导致。臭氧通过粘膜吸收入血后能活化细胞，调理气血从根本上解决上述问题； 5、自养保jian：臭氧对卵巢有良好保养功能，通过透皮吸收直接作用，能活化卵巢细胞，增强微循环，排除自由基，延缓卵巢衰老，维持卵巢的生理功能，平衡内分泌，减轻或推迟更年期。
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“直销同城网”南京大学姚祝军课题组 Yao Z.-J. Group Nanjing Univ.
The Yao Group
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Azepinoindole
Synthesis via a N‑Bromosuccinimide-Induced Cycloisomerization of
Enaminoester/Enaminone
Lina Chang, Tao
Guo, Ziyi Wang, Shaozhong Wang,and Zhu-Jun Yao
(DOI: 10.1021/acs.joc.6b02760)
Nodupetide, a
potent insecticide and antimicrobial from Nodulisporium sp. associated
with Riptortus pedestris
Hui Min Wu, Li Ping Lin, Qin Lan Xu, Wen
Bo Han, Song Zhang, Ze Wen Liu, Ya Ning Mei,Zhu Jun Yao,and Ren Xiang
（DOI.org/10.1016/j.tetlet.）
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addition-based cyclization strategy in the total synthesis of
Lycopodium alkaloids
Lin-Rui Zhong and Yao Zhu-Jun
(DOI:10.-016-0056-0)
Gram-Scale
Laboratory Synthesis of UM171, a Potent Agonist of Human Hematopoietic
Stem Cell Self-Renewal
Sajjad Ali,
Shun-Ming Yu,
and Zhu-Jun Yao
(DOI:10.1021/acs.joc.6b01094)
a-hydroxylation of b-keto esters and amides by co-catalysis of SmI3
and I2 under mild base-free conditions
Shun-Ming Yu, Kai Cui, Fei Lv , Zhen-Yu
Zhu-Jun Yao
(DOI:10.1016/j.tetlet.)
Convenient
One-Step Synthesis of Benzo[c]phenanthridines by Three-Component
Reactions of Isochromenylium Tetrafluoroborates and Stilbenes in
Acetonitrile
Gang-Gang Chen,&Jun-Qiang
Wei,&Xiaoliang
and&Zhu-Jun Yao
(DOI:&10.1021/acs.orglett.6b00010)
Enantioselective
Total Synthesis of Lycoposerramine-Z Using Chiral Phosphoric Acid
Catalyzed Intramolecular Michael Addition
Lan-De Zhang,&Lin-Rui
Zhong,&Jie
Xi,&Xiao-Liang
and&Zhu-Jun
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Kinetic or
Dynamic Control on a Bifurcating Potential Energy Surface?An
Experimental and DFT Study of Gold-Catalyzed Ring Expansion and
Spirocyclization of 2-Propargyl-β-tetrahydrocarbolines
Zhang Lei,Yi
Wang,Yao Zhu-Jun,Wang Shao-Zhong,Yu Zhi-Xing
(DOI:10.1021/jacs.5b05971)
Synthesis of
Tricyclo[4,3,1,01,5]decane Core of Plumisclerin A Using PausonCKhand
Annulation and SmI2-Mediated Radical Cyclization
Chen Ji-Peng,He
Wei,Yang Zhen-Yu,and Yao Zhu-Jun
(DOI:10.1021/acs.orglett.5b01563)
Synthesis of Octahydrophenanthrene Derivatives with Mild Cascade
Reactions of Isochromenylium Tetrafluoroborates and Bifunctional
Styrenes ,
Mo Lei, Wu
Lin-Lin,& Wang Shao-Zhong, Yao Zhu-Jun
(DOI:10.1021/acs.orglett.5b01532)
The last and next decades of the Asian Core Program on cutting-edge
organic chemistry in Asia
Minoru Isobe, Atsushi Nishida, Yeun-Mun Choo, Noorsaadah Abd. Rahman,
Poonsakdi Ploypradith, Somsak Ruchirawat, Guo-Qiang Lin, Ang Li, Zhu-Jun
Yao, Biing-Jiun Uang, Chun-Chen Liao, Pauline Chiu, Byeong Moon Kim,
Teck Peng Loh
Annonaceous acetogenin mimic AA005 induces cancer cell death via
apoptosis inducing factor through a caspase-3-independent mechanism
Han Bing, Wang Tong-Dan, Shen Shao-Ming, Yu Yun, Mao Chan, Yao Zhu-Jun,
Wang Li-Shun
2015, 15, 139
Short Protecting Group-free Syntheses of Camptothecin and
10-Hydroxycamptothecin Using Cascade Methodologies
Xu Peng, Chen Dong-Sheng Chen, Xi Jie, Yao Zhu-Jun
Stereodivergent total synthesis of chlorofusin and its all seven
chromophore diastereomers
Qiu Hai-Bo, Qian Wen-Jian, Yu Shun-Ming, Yao Zhu-Jun
2015, 71, 370-380
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Total Synthesis of Ascididemin-Type Alkaloids Using Alkyne Building
Yin Hao, Shan Naiyu, Wang Shaozhong, Yao Zhu-Jun
Total synthesis of proposed structure of coibamide A, a highly N- and
O-methylated cytotoxic marine cyclodepsipeptide
He Wei, Qiu Hai-Bo, Chen Yi-Jie, Xi Jie, Yao Zhu-Jun
Unified flexible total synthesis of chlorofusin and artificial Click
mimics as antagonists against p53CHDM2 interactions
Qiu Hai-Bo, Chen Xin-Ya, Li Qing, Qian Wen-Jian, Yu Shun-Ming, Tang
Gong-Li, Yao Zhu-Jun
Total Syntheses of Lycoposerramine-V and 5-epi-Lycoposerramine-V
Zhang Lan-De, Zhou Ting-Ting, Qi Sen-Xing, Xi Jie, Yang Xiao-Liang, Yao
Asymmetric Annulation of 3‑Alkynylacrylaldehydes with Styrene-Type
Olefins by Synergetic Relay Catalysis from AgOAc and Chiral Phosphoric
Zhang Hao, Zhu Le, Wang Shaozhong, Yao Zhu-Jun
Regio-controlled synthesis of unsymmetrical pyrazine-fused sinomenine
derivatives and discriminate substitution effects on TNF-α inhibitory
Zhou Tingting, Hou Jian, Wang Meng, Ma Liyan, Wu Linlin, Wang Shaozhong,
Sun Bing, Yao Zhu-Jun
cytotoxic annonaceous acetogenin mimetics having a nitrogen-heterocyclic
terminal and their application to cell imaging
Chen Yi-Jie, Jin Sheng, Xi Jie, Yao Zhu-Jun
synthesis of&ent-(−)-azonazine
using a biomimetic direct oxidative cyclization and structural
reassignment of natural product
Zhao Ji-Chen,Yu Shun-Ming,Qiu Hai-Bo,Yao Zhu-Jun
70. 3197C3210
Biological evaluation of new mimetics of annonaceous acetogenins:
Alteration of right scaffold by click linkage with aromatic
functionalities
Liu Yanghan, Xiao Qicai, Liu Yongqiang, Li Zheng, Qiu Yatao, Zhou
Guang-Biao, Yao Zhu-Jun, Jiang Sheng
2014. 78. 248-258
Identification of novel bivalent mimetics of annonaceous
acetogenins via a scaffold-hopping strategy
Liu Yanghan, Liu Yongqiang, Li Zhen, Zhou Guang-Biao, Yao Zhu-Jun, Jiang
24. 1650-1653
Azocinoindole Synthesis by a Gold(I)-Catalyzed Ring Expansion of
2-Propargyl-b-Tetrahydrocarboline
Zhang Lei, Chang
Lina, Hu Hongwen, Wang Huaqin, Yao Zhu-Jun, Wang Shaozhong
20, 2925-2932
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Assembly of indolo[1,2-c]quinazolines using ZnBr2-promoted domino
hydroaminationCcyclization
Xu Min, Xu Ke, Wang Shaozhong, Yao Zhu-Jun
适用于荧光成像的化学发色团与生物正交反应研究进展
张艳, 陈鹏, 姚祝军
Synthesis of 2-vinyl-2H-benzotriazoles via NIS-promoted regio/stereoselective
addition of 1H-benzotriazole to alkynes
Zhang ZhenHua, Chang Lina, Wang Shaozhong, Wang Huaqin, Yao Zhu-Jun
Biomimetic Synthesis of&ent-(−)-Azonazine and Stereochemical
Reassignment of Natural Product
Zhao Ji-Chen, Yu Shun-Ming, Liu Yun, Yao Zhu-Jun
Asymmetric Cascade Annulation Based on Enantioselective OxaDiels−Alder
Cycloaddition of in Situ Generated Isochromenyliums by Cooperative
Binary Catalysis of Pd(OAc)2 and (S)‑Trip
Yu Shu-Yan, Zhang Hao, Gao Yang, Mo Lei, Wang Shaozhong,& Yao Zhu-Jun
Asymmetric Michael addition of 4H-thiopyran-4-one to nitroolefins
catalyzed by diamine mono-N-sulfonamide and its application to concise
synthesis of enantiopure multiring heterocycles
Mo Lei, Tang Huang,& Yao Zhu-Jun
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule
Equilibrium and Inhibiting NF-κB Activation
Yu Zhao, Jia Su, Masuo Goto, Susan L. Morris-Natschke, Yan Li, Qin-Shi
Zhao, Zhu-Jun Yao, Kuo-Hsiung Lee
Asymmetric One-Pot Sequential Mannich/Hydroamination Reaction by Organo-
and Gold Catalysts: Synthesis of Spiro[pyrrolidin-3,2′-oxindole]
Derivatives
Chen Xianjie, Chen Hui, Ji Xun, Jiang Hualiang, Yao Zhu-Jun, Liu Hong
Organocatalytic enantioselective conjugate addition of
2-nitrocyclohexanone to acrylaldehyde: a concise two-step synthesis of
chiral building block 1-azaspiro[4.5]decan-6-one
Ding Xiao-Hua, Cui Wei-Chen, Li Xiang, Ju Xuan, Liu Dan, Wang Shaozhong,
Yao Zhu-Jun
Assembly of fused indenes via Au(I)-catalyzed C1CC5
cyclization of enediynes bearing an internal nucleophile
Hou Qiwen, Zhang Zhenhua, Kong Fanji, Wang Shaozhong, Wang Huaqin, Yao
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Sinomenine derivatives with embedment of
nitrogen-containing heterocycles exhibiting potent TNF-αinhibitory
Wang Meng, Ma Li-Yan, Lou Yang-Tong, Bian Chao, Zhou Ting-Ting, Zhou
Hai-Bin, Liao Hong-Ze, Ma Zhao, Yin Dong-Sheng, Wang Shaozhong, Yang
Zhen-Yu, Sun Bing, Yao Zhu-Jun
Assembly of pentacyclic pyrido[4,3,2-mn]acridin-8-ones
via a domino reaction initiated by Au(I)-catalyzed 6-endo-dig
cycloisomerization of N-propargylaminoquinones
Yin Hao, Kong Fanji, Wang Shaozhong, Yao Zhu-Jun
Gefitinib Analogue V1801 Induces Apoptosis of T790M
EGFR-Harboring Lung Cancer Cells by Up-Regulation of the BH-3 Only
Protein Noxa
Zhang Bo, Jiao Jiao, Liu Ying, Guo Liang-Xia, Zhou Bo, Li Gang-Qin, Yao
Zhu-Jun, Zhou Guang-Biao
Identification of an Annonaceous Acetogenin Mimetic,
AA005, as an AMPK Activator and Autophagy Inducer in Colon Cancer Cells
Liu Yong-Qiang, Cheng Xin, Guo Liang-Xia, Mao Chan, Chen Yi-Jie, Liu
Hai-Xia, Xiao Qi-Cai, Jiang Sheng, Yao Zhu-Jun, Zhou Guang-Biao
Highly Enantioselective Michael Addition of
2-Oxindole- 3-carboxylate Esters to Nitroolefins Promoted by Cinchona
Alkaloid-Thiourea-Br&nsted Acid Cocatalysts
Chen Xian-Jie, Zhu Wei, Qian Wangke, Feng Enguang, Zhou Yu, Wang
Jinfang, Jiang Hualiang, Yao Zhu-Jun, Liu Hong
Protecting Group-Free Total Synthesis of
(−)-Lannotinidine B
Ge Hui-Ming, Zhang Lan-De, Tan Ren-Xiang, Yao Zhu-Jun
Effect of Annonaceous Acetogenin Mimic AA005 on
Proliferative Inhibition of Leukemia Cells in vitro and Its Possible
Mechanisms
Han Bing, Yao Zhu-Jun, Wang Li-Shun
Enantioselective Total Synthesis of Marine Diterpenoid
Clavulactone
Yang Zhen-Yu, Liao Hong-Ze, Shen Kang, Chen Yong-Fei, Yao Zhu-Jun
Target-oriented multifunctional organocatalysis for
enantioselective synthesis of bicyclo[3.3.1]nona-2,6-dien-9-ones. A
formal asymmetric synthesis of huperzine A
Ding Xiao-Hua, Li Xiang, Liu Dan, Cui Wei-Chen, Ju Xuan, Wang Shaozhong, Yao Zhu-Jun
A simple selective protocol for continuous two-stage
fluorescent sensing of both MeHg+ and anti-MeHg+ agents in living cells
Mei De-Sheng, He Bao-Kun, Chen Lei, Yao Zhu-Jun
Br&nsted acid-promoted dimerization of
o-alkynylbenzaldehydes: a one-step synthesis of functionalized Kagan’s
ether analogues
Zhang Hao, Cui Wei-Chen, Hu Zhi-Long, Yu Shu-Yan, Wang Shaozhong, Yao Zhu-Jun
Electronically unfavorable addition of electron-deficient
olefins to isochromenylium tetrafluoroborates initiated by C-1
O-glycosylation
Yu Shu-Yan, Hu Zhi-Long, Zhang Hao, Wang Shaozhong, Yao Zhu-Jun
Regio- and stereoselective C10βCH functionalization of
sinomenine: an access to more potent immunomodulating derivatives
Lou Yang-Tong, Ma Li-Yan, Wang Meng, Yin Dongsheng, Zhou Ting-Ting, Chen
Ai-Zhong, Ma Zhao, Bian Chao, Wang Shaozhong, Yang Zhen-Yu, Sun Bing,
Yao Zhu-Jun
Concise synthesis of zanamivir and its C4-thiocarbamido
derivatives utilizing a [3+2]-cycloadduct derived from d-glucono-δ-lactone
Zhu Xue-Bin, Wang Meng, Wang Shaozhong, Yao Zhu-Jun
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Development of Novel Conformation-Constrained Cytotoxic
Derivatives of Cheliensisin A by Embedment of Small Heterocycles
Deng Xu, Su Jia, Zhao Yu, Peng Li-Yan, Yao Zhu-Jun, Zhao Qin-Shi
European Journal of Medicinal Chemistry,
Total Synthesis of 7-Ethyl-10-hydroxycamptothecin (SN38)
and its Application to the Development of C18-Functionalized
Camptothecin Derivatives
Yao Yuan-Shan, Liu Jia-Li, Xi Jie, Miu Bukeyan, Liu Guan-Sai, Wang
Shaozhong, Meng Linghua, Yao Zhu-Jun
Chemistry- A European Journal,
Modular assembly of cytotoxic acetogenin
mimetics by click linkage with nitrogen functionalities
Mao Chan, Han
Bing, Wang Li-Shan, Wang Shaozhong, Yao Zhu-Jun
MedChemComm,
2, 918-922.
CuCl(2)-Promoted 6-endo-dig
Chlorocyclization and Oxidative Aromatization Cascade: Efficient
Construction of 1-Azaanthraquinones from N-Propargylaminoquinones
Fei Na, Yin Hao,
Wang Shaozhong, Wang Huaqin, Yao Zhu-Jun
Efficient synthesis of furoquinolinones using Hendrickson
reagent-initiated cascade annulation
Xu Peng, Liu
Guan-Sai, Xi Jie, Wang Shaozhong, Yao Zhu-Jun
Tetrahedron,
Generation of trans-arachidonic acid under nitrative
stress is associated with upregulation of thromponsdin-1 in diabetic
Xu Lin, Liu
Yu-Min, Yao Zhu-Jun, Xun Guo-Liang, Yu Wen-Juan, Liu Kun, Sun Xiao-Dong,
Qiu Yun-Ping, Wu Hai-Xiang, Xu Xun
Chinese Medical Journal,
Evaluation of nitrative stress on retinal capillary by
detection of trans-arachidonic acid with GC/MS in diabetic rats
Xu Lin, Xun
Guo-Liang, Yao Zhu-Jun, Liu Yu-Min, Fan Ying, Sun Tao, Xu Xun
Chinese Journal of Experimental Ophthalmology,
29, 432-436.
Design, synthesis of symmetrical bivalent analogues
mimetics of annonaceous acetogenins and their cytotoxicities
Xiao Qi-Cai, Liu
Yong-Qiang, Qiu Ya-Tao, Yao Zhi-Yi, Zhou Guang-Biao, Yao Zhu-Jun, Jiang
Bioorganic & Medicinal Chemistry Letters,
Study on Iron-Catalyzed Oxidative Free Radical
Dimerization of Isochromenylium Tetrafluoroborate
Song Xiao-Nan,
Mo Lei, Hu Zhi-Long, Yang Zhen-Yu, Yao Zhu-Jun
Chimica Sinica,
69, 680-686.
Syntheses and characterizations of novel pyrrolocoumarin
probes for SNAP-tag labeling technology
Mei De-Sheng, Qu
Yi, He Jin-Xiang, Chen Lei, Yao Zhu-Jun
Tetrahedron,
Facile Assembly of 11H-Indolo[3,2-c]quinoline by a
Two-Step Protocol Involving a Regioselective 6-endo-Cyclization Promoted
by the Hendrickson Reagent
Xu Min, Hou
Qiwen, Wang Shaozhong, Wang Huaqin, Yao Zhu-Jun
Synthesis-Stuttgart,
4, 626-634.
Potent Antitumor Mimetics of Annonaceous Acetogenins
Embedded with an Aromatic Moiety in the Left Hydrocarbon Chain Part
Xiao Qi-Cai, Liu
Yong-Qiang, Qiu Ya-Tao, Zhou Guang-Biao, Mao Chan, Li Zheng, Yao
Zhu-Jun, Jiang Sheng
Journal of Medicinal Chemistry,
54, 525-533.
Fragmentations of 13-oxo-taxyunnansin A and their
application to preparation of abeo-paclitaxel and abeo-docetaxel
Zhao Yu, Zhang
Hong-Bin, Liu Ji-Kai, Su Jia, Li Yan, Yao Zhu-Jun, Zhao Qin-Shi
Tetrahedron Letters,
52, 139-142.
Three-Component Reactions of Isochromenylium
Tetrafluoroborates via Non-Classical [4+2]-Intermediates: Mild One-Step
Metal-Free Synthesis of Functionalized Dihydronaphthalenes and
Tetrahydronaphthalenes
Hu Zhi-Long,
Yang Zhen-Yu, Wang Shaozhong, Yao Zhu-Jun
Chemistry-A European Journal,
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Synthesis of Tetrahydroisoquinolines via Cascade
Reductive Amination of Isochromenylium Tetrafluoroborate with Primary
Liao Hong-Ze, Hu
Zhi-Long, Cui Kai, Jiao Jiao, Qin Yong, Yao Zhu-Jun
Synthesis-Stuttgart,
Efficient Synthesis of Phenanthridines Using Hendrickson
Reagent Initiated Cascade Reaction under Mild Conditions
Xi Jie, Dong
Qing-Li, Liu Guan-Sai, Wang Shaozhong, Chen Lin, Yao Zhu-Jun
Efficient Synthesis of Phenanthridines Using Hendrickson
Reagent Initiated Cascade Reaction under Mild Conditions
Jiang Chun-Hui,
Xu Min, Wang Shaozhong, Wang Huaqin, Yao Zhu-Jun
Journal of Organic Chemistry,
Synthesis of the cyclic nonapeptide of chlorofusin using
a convergent [3+3+3]-fragment coupling strategy
Wang Yan-Li,
Qian Wen-Jian, Wei Wan-Guo, Zhang Yue, Yao Zhu-Jun
Tetrahedron,
Short asymmetric synthesis of (S,S)-PDP using L-prolinol
derivative as economic starting material
Song Xiao-Nan,
Yao Zhu-Jun
Tetrahedron,
Direct nucleophilic C-1 addition of stable
isochromenylium tetrafluoroborates under catalyst-free conditions: A new
access to 1H-isochromenes
Hu Zhi-Long,
Qian Wen-Jian, Yao Zhu-Jun
Science China-Chemistry,
53, 869-876.
Total Synthesis of Chloptosin, a Potent
Apoptosis-Inducing Cyclopeptide
Yu Shun-Ming,
Hong Wen-Xu, Wu Yuan, Zhong Chun-Long, Yao Zhu-Jun
Modification of poorly bioactive sinomenine into more
potent immunosuppressive agents by embedding of drug-like fragments
Lou Yang-Tong,
Zhou Hai-Bin, Zou Jia, Yan Ling-Chen, Bi En-Guan, Sun Bing, Yao Zhu-Jun
Tetrahedron
51, 485-488.
Azaanthraquinone assembly from N-propargylamino quinone
via iodine-induced 6-endo-dig electrophilic cyclization
Fei Na, Hou
Qi-Wen, Wang Shaozhong, Wang Huaqin, Yao Zhu-Jun
& Biomolecular Chemistry,
Efficient Total Synthesis of (S)-14-Azacamptothecin
Liu Guan-Sai,
Yao Yuan-Shan, Xu Peng, Wang Shaozhong, Yao Zhu-Jun
Chemistry-An Asian Journal,
Synthesis of N(11)-anchoring biotinylated artemisinin
derivatives and their preliminary biological assessment
Pan Qi-Yu, Wang
Shaozhong, Lu JinJian, Meng Linghua, Yao Zhu-Jun
Science China-Chemistry,
53, 119-124.
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Construction of Multiring Frameworks by Metal-Free
Cascade Reactions of Stable Isochromenylium Tetrafluoroborate
Hu Zhi-Long,
Qian Wen-Jian, Wang Sheng, Wang Shaozhong, Yao Zhu-Jun
Journal of Organic Chemistry,
Transformation of Reactive Isochromenylium Intermediates
to Stable Salts and Their Cascade Reactions with Olefins
Hu Zhi-Long,
Qian Wen-Jian, Wang Sheng, Wang Shaozhong, Yao Zhu-Jun
Efficient Synthesis of
4-Amido-N(5)-acetyl-4-deoxyneuraminic Acid and Its Application to the
C-4 Modification of Sialic Acids
Gao Zheng-Xi,
Wang Meng, Wang Shaozhong, Yao Zhu-Jun
Stereoselective Synthesis of the Functionalized C2-C10
Fragment of Clavulactone
Zhou Zuo-Zhong, Suo Dong, Yang Zhen-Yu, Chen Lin, Hu Tai-Shan, Yao Zhu-Jun
Journal of Chemistry,
27, 135-140.
Expeditious Total Syntheses of Camptothecin and
10-Hydroxycamptothecin
Liu Guan-Sai, Dong Qing-Li, Yao Yuan-Shan, Yao Zhu-Jun
Organic Letters,
Development of New Pyrrolocoumarin Derivatives with
Satisfactory Fluorescent Properties and Notably Large Stokes Shifts
Chen Lei, Hu
Tai-Shan, Yao Zhu-Jun
European Journal of Organic Chemistry,
Site-Specific Fluorescent Labeling Approaches for
Naringenin, an Essential Flavonone in Plant Nitrogen-Fixation Signaling
Chen Lei, Li
Fen-Qing, Hou Bi-He, Hong Glio-Fan, Yao Zhu-Jun
Journal of Organic Chemistry,
Total synthesis of platensimycin: a review
Yao Yuan-Shan,
Yao Zhu-Jun
Chinese Journal of Organic Chemistry,
Biomimetic total syntheses of cassiarins A and B
Yao Yuan-Shan,
Yao Zhu-Jun
Journal of Organic Chemistry,
Synthesis of the biotinylated artemisinin derivative
Zhong Chun-Long,
Yao Zhu-Jun
Acta Chimica Sinica,
Metal-free synthesis of alkynyl imines using an
oxophosphonium-mediated approach at ambient temperatures
Dong Qing-Li,
Liu Guan-Sai, Zhou Hai-Bin, Chen Lin, Yao Zhu-Jun
Tetrahedron
Tuning the Acyclic Ether Moiety of Anticancer Agent AA005
with Conformationally Constrained Fragments
Liu Hai-Xia,
Shao Fei, Li Gang-Qin, Xun Guo-Liang, Yao Zhu-Jun
Chemistry-A European Journal,
<font size="2" face="Arial" color="#07
Short and efficient total synthesis of luotonin a and
22-hydroxyacuminatine using a common cascade strategy
Zhou Hai-Bin,
Liu Guan-Sai, Yao Zhu-Jun
Journal of Organic Chemistry,
An inexpensive fluorescent labeling protocol for
bioactive natural products utilizing Cu(I)-catalyzed Huisgen reaction
Zhang Yan-Hong,
Gao Zheng-Xi, Zhong Chun-Long, Zhou Hai-Bin, Chen Lei, Wu Wen-Min, Peng
Xin-Jun, Yao Zhu-Jun
Tetrahedron,
Annonaceous acetogenin mimics bearing a terminal lactam
and their cytotoxicity against cancer cells
Liu Hai-Xia,
Huang Guo-Rui, Zhang Huan-Ming, Wu Jia-Rui, Yao Zhu-Jun
Bioorganic & Medicinal Chemistry Letters,
Total synthesis, assignment of absolute stereochemistry,
and structural revision of chlorofusin
Qian Wen-Jian,
Wei Wan-Guo, Zhang Yong-Xia, Yao Zhu-Jun
Journal of the American Chemical Society,
Parallel synthesis of individual shikimic acid-like
molecules using a mixture-operation strategy and ring-closing enyne
metathesis
Hu Fang, Zhang
Yan-Hong, Yao Zhu-Jun
Tetrahedron
Highly efficient and mild cascade reactions triggered by
bis(triphenyl)oxodiphosphonium trifluoromethanesulfonate and a concise
total synthesis of camptothecin
Zhou Hai-Bin,
Liu Guan-Sai, Yao Zhu-Jun
<font size="2" face="Arial" color="#06
An efficient synthesis of selective human NR2A antagonist
NVP-AAM077
Li Gang-Qin, Su
Wei-Ke, Yao Zhu-Jun
Chinese Journal of Chemistry,
A concise synthesis of L-3-(o-methoxybenzoyl)alanine, a
selective kynurenine hydroxylase inhibitor
Ma Xiang-Dong,
Yao Zhu-Jun
Acta Chimica Sinica,
Bidirectional synthesis of the central amino acid of
chloptosin
Hong Wen-Xu,
Chen Ling-Jun, Zhong Chun-Long, Yao Zhu-Jun
Ring-closing metathesis-based synthesis of
(3R,4R,5S)-4-acetylamino-5-amino-3-hydroxycyclohex-1-ene-carboxylic acid
ethyl ester: A functionalized cycloalkene skeleton of GS4104
Cong Xin, Yao
of Organic Chemistry,
Bromoetherification-based strategy towards the
spirocyclic chromophore of chlorofusin
Wei Wan-Guo,
Qian Wen-Jian, Zhang Yong-Xia, Yao Zhu-Jun
Tetrahedron
Application of a regioselective Mannich reaction on
naringenin and its use in fluorescent labeling
Chen Lei, Hu
Tai-Shan, Zhu Jing, Wu Houming, Yao Zhu-Jun
Pauson-khand approach towards enantiopure C-2-symmetric
polycyclic compound from D-mannitol
He Y.-T., Xue
S., Yao Zhu-Jun
Acta Chimica Sinica,
64, 169-174.
Studies on natural cryptophycins and their mimetics: A
Zha H.-Y., Yao
Chinese Journal of Organic Chemistry,
26, 27-42.
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Efficient construction of novel alpha-keto spiro ketal
and the total synthesis of (+/-)-terreinol
Wei Wan-Guo,
Zhang Y.-X., Yao Zhu-Jun
Tetrahedron,
Preparation of enantiomerically pure 2-(1
'-aminomethyl)furan derivatives and synthesis of an unnatural
polyhydroxylated piperidine
Cong X., Liu
K.-G., Liao J., Yao Zhu-Jun
Tetrahedron
An iterative acetylene-epoxide coupling strategy for the
total synthesis of longimicin C
He Y.-T., Xue
S., Hu T.-S., Yao Zhu-Jun
Tetrahedron
Synthesis studies toward chloroazaphilone and vinylogous
gamma-pyridones: Two common natural product core structures
Wei Wan-Guo, Yao
of Organic Chemistry,
Chemoselective deprotection of cyclic N,O-aminals using
catalytic bismuth(III) bromide in acetonitrile
Cong X., Hu F.,
Liu K.-G., Liao Q.-J., Yao Zhu-Jun
Journal of Organic Chemistry,
Macrocyclization studies and total synthesis of
cyclomarin C, an anti-inflammatory marine cyclopeptide
Wen S.-J., Hu
T.-S., Yao Zhu-Jun
Tetrahedron,
Stereoselective synthesis of new modified
conformationally constrained L-tyrosine analogue with potential
applications to SH2 domain ligands
Liu F., Hu
T.-S., Yao Zhu-Jun
Tetrahedron,
Synthesis of a tetra-deuterium-labeled derivative of
potent and selective anticancer agent AA005
Liu H.-X., Yao
Tetrahedron
Synthesis of two naturally occurring 4-hydroxylated
butenolides with PTP1B inhibitory activity
Zhao Y., Jiang
S., Guo Y.-W., Yao Zhu-Jun
Chinese Journal of Chemistry,
23, 173-175.
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A chiron-based approach for the synthesis of tricyclic
tyrosine analogue
Liu F., Jiao J.,
Zha H.-Y., Yao Zhu-Jun
Chinese Journal of Chemistry,
RCM approaches toward the diastereoselective synthesis of
vicinal trans-diaminocyclitols from L-serine
Cong X., Liao
Q.-J., Yao Zhu-Jun
Journal of Organic Chemistry,
Total synthesis of cyclomarin C
Wen S.-J., Yao Zhu-Jun
Synthesis of 4-azido-4-deoxy-Neu5,7,8,9Ac(4)2en1Me. A key
intermediate for the synthesis of GG167 from D-glucono-delta-lactone
Liu K.-G., Yan
S., Wu Y.-L., Yao Zhu-Jun
Synthesis of
(2R,3aR,8aR)-6-chloro-3a-hydroxy-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic
acid methyl ester by reductive cyclization
Hong W.-X., Yao Zhu-Jun
Journal of Chemitry,
22, 365-370.
Parallel fragment assembly strategy towards
multiple-ether mimicry of anticancer annonaceous acetogenins
Jiang S., Li Y.,
Chen X.-G., Hu T.-S., Wu Y.-L., Yao Zhu-Jun
Angewandte Chemie-International Edition,
43, 329-334.
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Synthesis of a new stable conformationally constrained
2,7-anhydrosialic acid derivative
Liu K.-G., Zhou
H.-B., Wu Y.-L., Yao Zhu-Jun
Journal of Organic Chemistry,
Studies on the synthesis of
(2S,3R)-3-hydroxy-3-methylproline via C-2-N bond formation
Shen J.-W., Qin
D.-G., Zhang H.-W., Yao Zhu-Jun
Journal of Organic Chemistry,
Synthesis of a new conformation-constrained L-tyrosine,
analogue as a potential scaffold for SH2 domain ligands
Liu F., Zha
H.-Y., Yao Zhu-Jun
Journal of Organic Chemistry,
A practical procedure for multisubstituted beta-naphthols
and their derivatives
Wei W.-G., Yao Zhu-Jun
Tetrahedron,
An efficient enantioselective synthesis of the acyl side
chain of polyoxypeptins
Qin D.-G., Yao Zhu-Jun
Tetrahedron
44, 571-574.
Synthesis of a mimicking hybrid of Annonaceous acetogenin
with steroid for antitumoral activity investigation
Jiang S., Wu
Y.-L., Yao Zhu-Jun
Chinese Journal of Chemistry,
Sharpless AD strategy toward the gamma-methyl butenolide
unit of acetogenins: enantioselective synthesis of butenolide I and II
with mosquito larvicidal activity
He Y.-T., Yang
H.-N., Yao Zhu-Jun
Tetrahedron,
Recent progress of the synthetic study on sialic acid
(N-acetylneuaminic acid) and its analogs
Li L.-S., Liu
K.-G., Yao Zhu-Jun, Wu Yu-Lin
Chinese Journal of Organic Chemistry,
22, 718-734.
A new synthesis of Neu5Ac from D-glucono-delta-lactone
Liu Ke-Gang, Yan
Shi, Wu Yu-Lin, Yao Zhu-Jun
Journal of Organic Chemitry,
Synthesis of a fully protected (2S,3R)-N-(1 ',1
'-dimethyl-2 '-propenyl)-3-hydroxytryptophan from tryptophan
Wen S.-J., Zhang
H.-W., Yao Zhu-Jun
Tetrahedron
First synthesis of mosquito larvicidal butenolides I and
Jiang S., Wu
Yu-Lin, Yao Zhu-Jun
Journal of Chemistry,
20, 692-696.
Mimicry of annonaceous acetogenins: Enantioselective
synthesis of a (4R)-hydroxy analogue having potent antitumor activity
Jiang Sheng, Liu
Hai-Zhong, Sheng Gang, Zeng Bu-Bing, Cheng Xiao-Guang, Wu Yu-Lin, Yao Zhu-Jun
Journal of Organic Chemistry,
Enantioselective synthesis of
(2S,3R)-3-hydroxy-3-methylproline, a novel amino acid found in
polyoxypeptins
Qin Dong-Guang,
Zha Hui-Yan, Yao Zhu-Jun
Journal of Organic Chemitry,
Electronic effect of indolecarboxaldehyde in the
condensation with t-butyl bromoacetate promoted by biazaborolidine
Wen S.-J., Yao Zhu-Jun
Chimica Sinica,
60, 129-133.
List of Publications before&
Wu, Y.-L., Wu, W.-L., Yao, Z.-J., Li, Y.-L., Wang, Y.-F.,
Li, J.-C., Sun, X.-L., Peng, Z.-H., Yu, Q., Hu, T.-S., Zeng, B.-B.,
Wang, X.-Z. Syntheses of Enantiopure Natural Products from Sugars.
Chinese J. Org. Chem. 2001, 21, 1051.
Burke Jr.,T. R., Yao, Z.-J.,
Gao, Y., Wu, J. X., Zhu, X., Luo, J. H., Guo, R., Yang, D. N-Terminal
Carboxyl and Tetrazole-Containing Amides as Adjuvants to Grb2 SH2 Domain
Ligand Binding. Bioorg. Med. Chem. 2001, 9,
Burke Jr., T. R., Yao,
Z.-J., Liu, D.-G., Voigt, J., Gao, Y. Phosphoryltyrosyl Mimetics in
the Design of Peptide-Based Signal Transduction Inhibitors.
Biopolymers 2001, 60, 32-44.
Wu, Y.-L., Chen, H.-B., Jiang, K., Li, Y., Shan, F., Wang, D.-Y.,
Wang, Y.-F., Wu, W.-M., Wu, Y., Yao, Z.-J., Yue, Z.-Y., Zhou,
C.-M. Interaction of biomolecules with qinghaosu (artemisinin)
and its derivatives in the presence of ferrous ion C an exploration of
antimalarial mechanism. Pure Appl. Chem. 1999, 71,
Burke, T. R., Jr., Gao, Y., Yao, Z.-J., Voigt, J., Luo,
J., Yang, D. Potent non phosphate-containing Grb2 SH2 domain inhibitors.
Pept. Sci. 1999, 36, 49-52.
& 46.Yao, Z.-J.,
Zhang, Y.-B., Wu, Y.-L. Synthesis of annonaceous acetogenin (4S, 5S)
and (4S, 5R)-muricatacin as well as confirmation of absolute
configuration of the tetrahydrofuran segment of annonacin. Acta
Chim. Sinica 1992, 50, 901.
Office E515, Lab
B505 511 512, School of Chemistry and Chemical Engineering
