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The owner of this website (enc.tfode.com) has banned your access based on your browser's signature (44d43b1d416e77b4-ua98).Protein knowledgebaseSequence archiveHelp pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects.Sequence clustersProtein sets from fully sequenced genomesAnnotation systemsSystems used to automatically annotate proteins with high accuracy:Supporting dataSelect one of the options below to target your search:You are using a version of browser that may not display all the features of this website. Please consider upgrading . Putative ATP-dependent RNA helicase DHX30Dhx30Rattus norvegicus (Rat)-Annotation score: -Experimental evidence at protein leveliFunctioniPlays an important role in the assembly of the mitochondrial large ribosomal subunit (By similarity). Associates with mitochondrial DNA (By similarity). Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (PubMed:).Manual assertion inferred from sequence similarity toiManual assertion based on experiment ini"DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein.", , , ,
[] [] []Cited for: FUNCTION, IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH ZC3HAV1.Catalytic activityiATP + H2O = ADP + phosphate.RegionsFeature keyPosition(s)DescriptionActionsGraphical viewLengthNucleotide bindingiATPManual assertion according to rulesi8GO - Molecular functioniGO - Biological processiKeywordsiMolecular function, , Biological processLigand, Names & TaxonomyiProtein namesiRecommended name:Putative ATP-dependent RNA helicase DHX30 (EC:)Alternative name(s):DEAH box protein 30Gene namesiName:OrganismiTaxonomic identifieri
[]Taxonomic lineagei >
Proteomesi Componenti: Chromosome 8 Organism-specific databasesRGDi Dhx30Subcellular locationi
Extracellular region or secreted
Plasma membrane
Cytoskeleton
Peroxisome
Golgi apparatus
Mitochondrion
Manual annotation
Automatic computational assertionGraphics by Christian S Source: Keywords - Cellular componenti, , PTM / ProcessingiMolecule processingFeature keyPosition(s)DescriptionActionsGraphical viewLengthChainiPRO_Putative ATP-dependent RNA helicase DHX30 1194Amino acid modificationsFeature keyPosition(s)DescriptionActionsGraphical viewLengthModified residueiPhosphoserineManual assertion inferred from sequence similarity toi1Modified residueiPhosphoserineManual assertion inferred from combination of experimental and computational evidencei"Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", , , , , ,
[] [] []Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].1Modified residueiPhosphoserineManual assertion inferred from sequence similarity toi1Keywords - PTMiProteomic databasesPaxDbiPRIDEiPTM databasesiPTMnetiPhosphoSitePlusiExpressioniGene expression databasesBgeeiExpressionAtlasi baseline and differentialGenevisiblei RNInteractioniSubunit structureiIdentified in a complex with TFAM and SSBP1 (By similarity). Interacts (via N-terminus) with ZC3HAV1 (via N-terminal domain) in an RNA-independent manner. Found in a complex with GRSF1, DDX28, FASTKD2 and FASTKD5 (By similarity).Manual assertion inferred from sequence similarity toiManual assertion based on experiment ini"DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein.", , , ,
[] [] []Cited for: FUNCTION, IDENTIFICATION BY MASS SPECTROMETRY, INTERACTION WITH ZC3HAV1.Protein-protein interaction databasesSTRINGiStructurei3D structure databasesProteinModelPortaliSMRiModBaseiMobiDBiFamily & DomainsiDomains and RepeatsFeature keyPosition(s)DescriptionActionsGraphical viewLengthDomainiDRBM 69DomainiHelicase ATP-bindingManual assertion according to rulesi 169DomainiHelicase C-terminalManual assertion according to rulesi 174MotifFeature keyPosition(s)DescriptionActionsGraphical viewLengthMotifiDEAH box4Compositional biasFeature keyPosition(s)DescriptionActionsGraphical viewLengthCompositional biasiPoly-Glu 12Compositional biasiPoly-Glu4Sequence similaritiesiBelongs to the . .Phylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOGENOMiHOVERGENiInParanoidiKOiOMAiOrthoDBiFamily and domain databasesCDDi HELICc, 1 hitInterProi DEAD/DEAH_box_helicase_dom DNA/RNA_helicase_DEAH_CS DUF1605 Helicase-assoc_dom Helicase_ATP-bd Helicase_C P-loop_NTPasePfami DEAD, 1 hit HA2, 1 hit Helicase_C, 1 hit OB_NTP_bind, 1 hitSMARTi DEXDc, 1 hit HA2, 1 hit HELICc, 1 hitSUPFAMi SSF52540, 1 hitPROSITEi DEAH_ATP_HELICASE, 1 hit HELICASE_ATP_BIND_1, 1 hit HELICASE_CTER, 1 hitSequenceiSequence statusi: Complete.Q5BJS0-1 []
50MFTLDSFRKD RTQHRQRQCK LPPPRLPPMC VNPAPGGTIS RASRDLLKEF
100PQPKNLLNSV IGRALGISHA KDKLVYVHTN GPKKKKVTLH IKWPKSVEVE
150GYGSKKIDAE RQAAAAACQL FKGWGLLGPR NELFDAAKYR VLADRFGSPA
200DSWWRPEPTM PPTSWRQLNP ENIRPAGTGG LSRSLGREEE EDEEEELEEG
250TIDVTEFLSM TQQDSHNPLR DSRGGSFEMT DDDSAIRALT QFPLPKNLLA
300KVIQIATSSS TAKNLMQFHT VGTKTKLATL TLLWPCPMTF VAKGRRKAEA
350ENKAAALACK KLKSLGLVDR NNEPLTHAMY NLASLRELGE TQRRPCTIQV
400PEPILRKIEA FLSHYPVDSS WISPELRLQS DDILPLGKDS GPLSDPITGK
450PYMPLSEAEE VRLSQSLLEL WRRRGPIWQE APQLPVDPHR DTILSAIEQH
500PVVVISGDTG CGKTTRIPQL LLERYVTEGR GARCNVIITQ PRRISAVSVA
550QRVSHELGPS LRRNVGFQVR LESKPPARGG ALLFCTVGIL LRKLQSNPSL
600EGVSHVIVDE VHERDVNTDF LLILLKGLQR LNPALRLVLM SATGDNERFS
650RYFGGCPVIK VPGFMYPVKE HYLEDILAKL GKHQYPHRHR HHESEDECAL
700DLDLVTDLVL HIDARGEPGG ILCFLPGWQE IKGVQQRLQE ALGMHESKYL
750ILPVHSNIPM MDQKAIFQQP PLGVRKIVLA TNIAETSITV NDIVHVVDSG
800LHKEERYDLK TKVSCLETVW VSRANVIQRR GRAGRCQSGF AYHLFPRSRL
850EKMVPFQVPE ILRTPLENLV LQAKIHMPEK TAVEFLSKAV DSPNIKAVDE
900AVILLQEIGV LDQREYLTTL GQRLAHISTD PRLAKAIVLA AIFRCLHPLL
950VVVSCLTRDP FSSSLQNRAE VDKVKALLSH DSGSDHLAFV RAVAGWEEVL
1000RWQDRTSREN YLEENLLYAP SLRFIHGLIK QFSENIYEAF LVGKPSDCTL
1050PSAQCNEYSE EEELVKGVLM AGLYPNLIQV RQGKVTRQGK FKPNSVTYRT
1100KSGNILLHKS TINREATRLR SRWLTYFMAV KSNGSVFVRD SSQVHPLAVL
1150LLTDGDVHIR DDGRRATISL SDSDLLRLEG DSRTVRLLRE LRRALGRMVE
1190 RSLRSELAAL PLSVQQEHGQ LLALLAELLR GPCGSFDVRK TADD
1,194133,997April 12, 2005 - v1Checksum:iA453E243EB1A5929BLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutterSequence databasesSelect the link destinations:EMBLiGenBankiDDBJi mRNA Translation: RefSeqi, , , , UniGeneiGenome annotation databasesEnsembli; ; GeneIDiKEGGiUCSCi ratSimilar proteinsi1194128412771265126511941284127712651265 mRNA Translation: RefSeqi, , , , UniGenei3D structure databasesProteinModelPortaliSMRiModBaseiMobiDBiProtein-protein interaction databasesSTRINGiPTM databasesiPTMnetiPhosphoSitePlusiProteomic databasesPaxDbiPRIDEiProtocols and materials databasesStructural Biology KnowledgebaseGenome annotation databasesEnsembli; ; GeneIDiKEGGiUCSCi ratOrganism-specific databasesCTDiRGDi Dhx30Phylogenomic databaseseggNOGi Eukaryota LUCAGeneTreeiHOGENOMiHOVERGENiInParanoidiKOiOMAiOrthoDBiMiscellaneous databasesPROiGene expression databasesBgeeiExpressionAtlasi baseline and differentialGenevisiblei RNFamily and domain databasesCDDi HELICc, 1 hitInterProi DEAD/DEAH_box_helicase_dom DNA/RNA_helicase_DEAH_CS DUF1605 Helicase-assoc_dom Helicase_ATP-bd Helicase_C P-loop_NTPasePfami DEAD, 1 hit HA2, 1 hit Helicase_C, 1 hit OB_NTP_bind, 1 hitSMARTi DEXDc, 1 hit HA2, 1 hit HELICc, 1 hitSUPFAMi SSF52540, 1 hitPROSITEi DEAH_ATP_HELICASE, 1 hit HELICASE_ATP_BIND_1, 1 hit HELICASE_CTER, 1 hitProtoNetiMiscellaneousiKeywords - Technical termi, DocumentsIndex of protein domains and familiesWe'd like to inform you that we have updated our
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