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Zetasizer Nano Z
Further information:
The Zetasizer Nano Z system is dedicated to the measurement of zeta potential and electrophoretic mobility in aqueous and non-aqueous dispersions using Laser Doppler Micro-Electrophoresis.
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The Zetasizer Nano Z is the perfect system for measuring zeta potential and electrophoretic mobility of colloids and nanoparticles, when the measurement of size or molecular weight is not required.
Zeta potential using patented M3-PALS technology.
A ‘Quality Factor’ and ‘Expert Advice System’ gives the confidence of having an expert at your shoulder.
21CFR part 11 software option to enable compliance with ER/ES.
Research software option to give access to further features and analysis algorithms for the light scattering specialist.
Automation of measurements using an autotitrator option.
Alternative laser, 50mW at 532nm for samples incompatible with the standard 633nm laser.
Optical filter option to improve measurements with fluorescent sample.
Temperature range extension option to 120°C.
The Zetasizer Nano Z uses micro-electrophoresis / electrophoretic light scattering technology to measure zeta potential and electrophoretic mobility.
Laser Doppler Micro-electrophoresis is used to measure zeta potential. An electric field is applied to a solution of molecules or a dispersion of particles, which then move with a velocity related to their zeta potential. This velocity is measured using a patented laser interferometric technique called M3-PALS (Phase analysis Light Scattering). This enables the calculation of electrophoretic mobility, and from this, the zeta potential and zeta potential distribution.
The software is designed to be versatile and rich in features without compromising ease of use. Standard Operating Procedures (SOP) simplify routine measurements, a quality factor gives a single place for confirmation of data quality, and an expert advice system is provided to assist with data interpretation.
The MPT-2 Autotitrator enables the study of the effect of changes in pH, conductivity, or any additive to be automated.
A range of disposable and reusable cells are available to optimize the measurement in terms of sample volume, concentration and flow measurement.
Other options include filters to improve the measurement of fluorescent samples, a temperature range extension to 120?C and a viscometer to determine the sample viscosity to the accuracy required for the techniques used.
Zeta potential
Measurement range:
3.8nm – 100 microns* (diameter)
Measurement principle:
Electrophoretic Light Scattering
Minimum sample volume:
150uL (20uL using diffusion barrier method).
0.12um.cm/V.s for aqueous systems using NIST SRM1980 standard reference material.
Sensitivity:
10mg/mL (BSA)
Temperature control range:
0°C - 90°C +/-0.1**, 120°C option.
Light source:
He-Ne laser 633nm, Max 4mW.
Laser safety:
Weight and dimensions:
Dimensions (W, D, H):
320mm, 600mm, 260mm (W,D,H)
Operating environment:
Operating temperature (°C):
10°C – 35°C
35% - 80% non-condensing
maximum range, sample dependent
The Zetasizer Nano range is protected by the following patents:
Non-Invasive Back Scatter (NIBS)
EP884580, US6016195, JP
High and Low Frequency Electrophoreses (M3)
EP1154266, US7217350, JP
Light Scattering Measurements using Simultaneous Detection
EP2235501, CN, JP, US
Surface Potential Determination in a Dip Cell
A range of accessories are available to make life easier, or to add capability to the system
Accessories
Simplify pH, conductivity and additive titrations on your Zetasizer Nano
A cost effective accessory designed to automate the measurement of size and zeta potential as a function of pH, conductivity or any soluble additive.
Viscosity measurement with speed, simplicity and accuracy.
The SV-10 measures viscosity with the accuracy required for dynamic light scattering, for the conversion of diffusion speed to size, and electrophoretic mobility to zeta potential, in an extremely simple and rapid system.
Cell and cuvette options
Disposable folded capillary cell (DTS1070)
Eliminate sample cross contamination between zeta potential measurements using a completely disposable cell.
The zeta potential of colloids and molecules is extremely sensitive to contamination from components of a previous sample used in a measurement cell. The use of a disposable cell completely eliminates this potential contamination issue.
The folded capillary cell provides the benefits of the accuracy of measurement of a capillary cell with the ease of use of a disposable cell.
Although, disposable, including the electrodes, for low conductivity samples each cell can be used for hundreds of measurements if required.
The cell can be used with the autotitrator, where multiple measurements are routinely done over a wide pH range.
Universal 'dip' cell kit
Reusable solvent resistant cell.
The dip cell is used for the measurement of zeta potential of samples in aqueous and non-aqueous dispersants, and is designed to be cleaned and reused. It is for batch measurements using standard polystyrene or glass cuvettes.
High concentration zeta potential cell kit
Save time and effort by measuring zeta potential with little or no dilution.
The high concentration cell enables the measurement of the zeta potential of samples with little or no dilution in any Zetasizer Nano system that measures zeta potential.
The cell has a flow configuration so can be used for stop-flow size and zeta potential measurements using an MPT-2 autotitrator as well as batch measurements.
Surface zeta potential accessory
Extend the application of the Zetasizer Nano to measure the zeta potential of material surfaces.
The characterization of surfaces and interfaces is critical in a wide range of industries including consumer products, specialty chemicals, pharmaceuticals and life sciences. In each of these application areas, the interaction of molecules and particles with surfaces can influence the material properties of the end product.
The surface zeta potential accessory enables the measurement of the zeta potential of flat surfaces such as filter paper, silica, polymers and bone, using a standard Zetasizer Nano system.
Quartz flow cell (ZEN0023)
Add flow capability for size measurements to the Zetasizer.
Measure size and intensity with MPT-2 autotitrator.
Connect to an SEC system to use as a DLS detector.
12mm Glass cell (PCS1115)
Glass cuvette for use with the dip cell.
For size and zeta potential measurements using the ‘dip’ cell.
Compatible with aqueous and non-aqueous solvents and dispersants.
Factory fitted options
50mW 532nm DPSS laser
For use where the sample is incompatible with the standard 633nm laser, either because the sample absorbs or fluoresces, or the sample is photosensitive.
This addition of this option does not affect the system specifications.
Narrow band filters
Useful where the sample fluoresces. Eliminates scattering due to fluorescence to improve the signal to background ratio.
High temperature capability
Increases the high temperature capability from 90°C to 120°C. Suitable for samples in wax media that melt above 90°C.
Degasser for MPT-2 autotitrator
Titrants used by the MPT-2 titrator need regular degassing, ideally before each titration.
Degassing is required to remove bubbles that can affect the volume of titrant dispensed. This is particularly important close to pH 7 where low volumes of titrant are required.
The degasser is a highly recommended ‘Fit and forget’ accessory that continuously degasses titrants which improves the speed of titrations and the accuracy of reaching the target pH. This gives more evenly spaced pH points.
Protect your investment and ensure optimized performance at all times with Malvern’s service plans.When you purchase a Malvern product we understand that this is just the first stage of a working relationship that will last for the lifetime of the instrument. Depending on your needs, Malvern will provide the support for your business.Help Desk.Operators who take responsibility for your call and ensure your query is answered. TrainingE-learningSoftware downloadsMalvern’s service options- choose the right plan for you:Malvern Platinum PlanFor laboratories where maximizing instrument up-time is critical to its daily performance. Our highest level of response and the 'all inclusive' price plan takes care of those unexpected repair bills should the unfortunate occur.Malvern Gold PlanEnhance your laboratory productivity by maintaining instrument efficiency. Still receive that priority response, combined with specialist technical and software support, we'll keep your instrument performance on track to deliver.Malvern Bronze VisitFor laboratories looking to optimize instrument performance, regular preventative maintenance is essential.Platinum PlanGold PlanBronze VisitAnnual PM/PV TestyesyesnoTelephone / Email SupportyesyesnoPriority ResponseyesyesnoEmergency Breakdown visits*yesyesnoParts IncludedyesnonoE-Learning**yesyesnoTechnical & Software SupportyesyesyesIQ/OQ (Pharma)***yesyesyes*including labour & travel costs** Platinum 2 places per contract term, Gold 1 place per contract term***available at an additional cost
Particle size analysis is important in many industries. Knowledge of particle size is important in the food industry because it affects the production and handling of ingredients and the formulation, processing, and quality control of food and bevera...
Electrophoretic light scattering (ELS) or zeta potential instruments use first principles in their measurement protocol. They cannot therefore, be calibrated. However, they can be verified that they are operating correctly, by measuring a suitable zeta potential standard.
Samples for zeta potential measurements need to be optically clear and may require dilution. The way in which the dilution is performed is absolutely critical in determining the zeta potential value measured.
Multiple scattering refers to the phenomenon where photons scattered from the sample are re-scattered from neighboring particles prior to reaching the instrument detector.
A correlation function shows the correlation coefficients plotted as a function of delay time
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All information supplied within is correct at time of publication.
Malvern Instruments pursues a policy of continual improvement due to technical development. We therefore reserve the right to deviate from information, descriptions, and specifications in this publication without notice. Malvern Instruments shall not be liable for errors contained herein or for incidental or consequential damages in connection with the furnishing, performance or use of this material.
Malvern and the 'hills' logo, Bohlin, Gemini, Insitec, ISys, Kinexus, Mastersizer, Morphologi, Rosand, SyNIRgi, Viscotek and Zetasizer, are International Trade Marks owned by Malvern Instruments Ltd.小木虫 --- 500万硕博科研人员喜爱的学术科研平台
&&查看话题
关于沉淀颗粒的粒径与电位的检测
我用CaCl2和Na2SO3反应生成CaSO3沉淀，考察空化时间对生成的亚硫酸钙的影响。用Zetasizer&&Nano ZS90测沉淀颗粒的粒径与电位。有谁知道如何处理样品？测粒径和电位用什么分散剂？我用的是十二烷基苯磺酸钠（阴离子表面活性剂），但对颗粒的电位影响太大，但不加分散剂又不能测，是不是得加一种非离子表面活性剂呢？但又不知加什么？谢谢
谢谢，我加上分散剂测得的亚硫酸钙的沉淀颗粒的粒径是几百纳米有时是一千多纳米。不加分散剂的话一会就沉淀，仪器测量就不准。测粒径和电位的话，静置后测清液的粒径和电位能代表亚硫酸钙沉淀颗粒的粒径和zeta电位吗？对颗粒的zeta电位的含义不是很明白。
谢谢，如果我考察亚硫酸钙沉淀颗粒的zeta电位，得在同一ph下分别测电位。用非离子表面活性剂分散亚硫酸钙沉淀颗粒，是不是对颗粒的电位无影响，我查的非离子表面活性剂是在水中不电离。还有沉淀颗粒的电位的大小说明什么？对这些知识不是很明白。
一两句说不清楚，找本表面化学书看看。
这么大的颗粒，自然是很容易沉淀的...但加离子型分散剂肯定会影响测试结果，非离子型的可以试试~~
清液的粒径是体系中分散性最好的那部分颗粒的粒径，跟全部离子真实粒径会有一定偏差（甚至很大偏差）~
至于zeta电势，确实不容易说明白，简单理解就是：水合（溶剂合）颗粒表面电荷的一种度量，其值与颗粒粒径、颗粒表面荷电基团数量、类型均有关系，但难于建立普适而明确的数学关系（不知现在是否还是这样...）~
恩，好的，谢谢
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Malvern Instruments Ltd.
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Zetasizer Nano系列纳米粒度和Zeta电位仪
产品型号：Zetasizer Nano系列
信息完整度：关注度：20634
新一代Zetasizer Nano 系列可以为胶体和聚合物化学专家提供综合测量三项最重要参数的能力，即粒度、zeta 电位和分子量。
这些系统中内置了新技术，提供无比的灵敏性和多功能性。
粒度 - NIBS 技术可以对粒径范围0.3 纳米至 10 微米的颗粒和分子进行测量。
Zeta 电位 - M3-PALS 技术能够对水分散和非水分散体系中的 zeta 电位进行精确的测量。
分子量 - 雪崩光电二极管检测器和光纤检测光学装置提供测量绝对分子量所需的灵敏度和稳定性。
Zetasizer Nano 系列中,可根据实际应用选择Nano ZS, Nano ZS90, Nano S, Nano Z,Nano S90等不同型号
Zetasizer Nano ZS 是 Malvern Zetasizer Nano 系列中的佼佼者，能够测量所有三项参数，而且性能丝毫不减。
Nano ZS、Z 及 ZS90 都可以使用独特的一次性 zeta 电位样品池，避免样品之间的交叉污染。
所有系统均可与 MPT-2 自动滴定仪连接使用，实现趋势测量和样品制备的自动化。
新一代Zetasizer Nano系列纳米粒度和Zeta电位及分子量分析仪
持续革新与优化 树立纳米分析新标杆
融合多项专利技术 挑战颗粒表征极限
粒度范围极宽:0.3-- 10 &m
浓度范围广: 0.1ppm&40%(w/v)
测量绝对分子量
高分辨率高灵敏度Zeta电位测量&
最新专利zeta电位样品池具有所需样品量低至150 &l 和检测高浓度样品最高至40%(依赖于样品)的极限能力
技术参数：
最大粒径范围: 0.3 nm - 10 &m *
浓度范围: 0.1ppm & 40% w/v *
检测角度: 175& 和 12.8&
最小样品量: 12 &l
Zeta电位测量
Zeta电位范围: 无实际限制
电泳迁移率: 0 & 无实际上限
最大样品电导率: 200mS/cm
最大样品浓度: 40% w/v
最小样品量: 150 &l
粒径范围: 3.8nm - 100 &m *
分子量测量
分子量范围 342 - 2 &107 Da * (动态光散射)&
&&&&&&&&&&&980 - 2 &107 Da * (静态光散射)
最小样品量 12 &l，* 取决于样品&
多项专利技术
 马尔文专利NIBS非侵入背侧光散射技术使仪器具有最高灵敏性
 马尔文专利的新一代PALS+M3技术,将最优的硬件与软件技术相结合,有效检测散射光的相位变化
 马尔文专利的毛细管样品池电极组件,真正避免交叉污染
强大多功能系统
 世界公认最优的APD检测器,灵敏度无出其右
 特制高性能He-Ne激光器,提供更高的稳定性
 标准配置研究级高速数字相关器
&#6度和12.8度相结合的双角度测量模式,洞悉体系中的缔合物含量&
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对该产品感兴趣，请留言！
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我对您的Zetasizer Nano系列纳米粒度和Zeta电位仪产品感兴趣，请发具体的信息及报价，谢谢！Cell Cleaning Movie
of new zeta potential capillary cell wash and filling procedures.
Recent Upgrade:
: Zetasizer software was upgraded to v. 6.20.
Malvern Zetasizer Nano ZS
Malvern Zetasizer combined 3 major techniques:
1. Dynamic Laser Scattering for Particle Size measurement
2. Static Laser Scattering for Mw measurement
3. Zeta-potential measurement
Equipped with MPT-2 autotitrator and temperature control system, the Zetasizer Nano is capable for pH titration, sample dilution and injection, temp. trend measurements and melting point studies.
Please refer to
to learn more about zetasizer.
Important Notification:
* () Cuvettes should be rinsed and sonicated in your buffers and/or ddH2O before applying samples for measurements.
* () Please avoid dusts or contaminate when preparing your sample. Do not transfer samples from container to container, which introduces dusts and bubbles.
Dynamic Light Scattering*
Dynamic light scattering (DLS) also known as Photon Correlation Spectrpscopy (PCS). By detecting the laser scattered from solution, the velocity of Brownian motion could be used for calculating the size of the particle. Please refer to
at Malvern website for details.
Static Light Scattering
Like DLS, Static light scattering (SLS) also measures the scattered light. But, instead of measuring the time-dependent fluctuations in the scattering intensity,
SLS makes use of the time-averaged intensity of scattered light instead.
When particles in solution are much smaller than the wavelength of the incident light,
the angular dependence of the scattering intensity is lost.
The type of scattering is known as .
The intensity of scattered light produced by particles is propotional to the product of weight-average Mw and the concentration of the particle.
By measuring the Intensity of scattered light of various concentration at 1 angle,
the Debye Plot is presnt to allow the determination of both absolute Mw and 2nd Virial Coefficient.
Zeta Potential
The net charge at the particle surface affects the distribution of ions in the surrounding, thus forming an electrical double layer around each particle.
When a particle moves, ions within the boundary move with it, and vice versa.
is the potential that exists at this boundary.
The intensity of the Zeta potential is an indication of the potential stability in the collidal system.
Particles with zeta potentials between +30mV and -30mV are normally considered unstable. .
* Pictures adepted from Manuals of manufacturer.
Specification
Laser wavelength
Particle size range
0.6nm - 6μm
size range for zeta potential
5nm - 10μm
size range for Mw
1000 - 2x10^7 Da
sample volume
Temperature range
Recommended Sample concentration
Particle size
Min. concentration
Max. concentration
---------------
10nm - 100nm
100nm - 1μm
0.1g/l (0.01% mass)您所在位置： &
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