鸡喉气管狭窄的治疗与鸡新城1系合用产生什么反应

加盟华强 共创辉煌
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鸡新城疫(Avian&Newcastle&Disease,&ND)是由新城疫病毒(Newcastle&disease&virus,NDV)引起的一种高度接触性、败血性传染病,主要特征是下痢、呼吸困难、神经机能紊乱、黏膜和浆膜出血。该病于1926年首次发生于印度尼西亚的爪哇岛,同年又在英国新城爆发,故命名为新城疫。我国最早是1935年在河南省检测到鸡新城疫病原,此后该病一直是威胁我国养鸡业发展的最严重疫病之一,给养鸡业带来了巨大的经济损失。&&&&&一、病原学&&&&&&新城疫病毒(Newcastle&disease&virus,NDV)属于副黏病毒科腮腺炎病毒属(Rubulavirus),完整病毒粒子近圆形,有囊膜,在囊膜的外层呈放射状排列的突起物或称纤突。能在鸡胚内繁殖,也可在细胞上培养,引起细胞病理变化,使感染细胞形成空斑。该病毒具有血凝素,可与红细胞表面受体结合,引起红细胞凝集。可凝集多种动物(如鸡、绵羊、豚鼠等)的红细胞,且这种凝集可被抗新城疫血清特异性抑制。因此,利用这一特点可进行新城疫诊断、测定疫苗的免疫效果和流行病学调查等。&&&&&大量试验已证明,尽管目前尚未发现新城疫病毒的不同血清型,但在不同地区新城疫毒株的抗原性存在差异,各毒株的毒力有很大变化。根据编码F蛋白基因的不同,可将新城疫病毒分为9个基因型群体,即基因I型、II型、III型、IV型、V型、VI型、VII型、VIII型、IX型。根据其毒力不同可将新城疫病毒分为三类,即弱毒株、中强毒株和强毒株。&新城疫病毒的抵抗力不强,容易被干燥、日光及腐败杀死。但在阴暗潮湿、寒冷的环境中,病毒生存时间较长。在掩埋的尸体和土壤中,能生存1个月。在室温或高温条件下,存活期较短。常用的消毒药,如2%氢氧化钠溶液、3%石炭酸溶液和1%来苏儿等消毒药,3分钟内都能杀死病毒。&&&&&&二、流行病学&&&&&&鸡最易感,不分品种、年龄和性别,均可发生,火鸡、鹌鹑、鸽等亦可感染发病。鸭、鹅等水禽及麻雀、乌鸦等飞禽也可散布病毒。该病一年四季均可发生,尤以寒冷和气候多变季节多发。病鸡是本病的主要传染来源,在其出现症状前24小时,即可由口、鼻分泌物和粪便中排出病毒,在症状消失后5~7天停止排毒。轻症病鸡和临床健康的带毒鸡,也是危险的传染源。病毒存在于病鸡的所有组织器官、体液、分泌物和排泄物中。&&&&&该病主要通过消化道和呼吸道传染,污染的饲料、饮水、空气和尘埃都可传染本病,也有的通过眼结膜、创伤和交配而传染,但最大的潜在散播者是人和器具。当鸡抵抗力低时可使鸡群80%以上的鸡只感染发病,90%以上的病鸡死亡和淘汰。&&&&&三、临床症状&&&&&在免疫鸡群中,由于多种因素造成的群体免疫力不均衡而发生非典型新城疫。育雏和育成阶段发生时,首先表现的是呼吸症状,夜间可见鸡群有明显的呼吸音,有的鸡表现为呼吸困难,伸颈张口喘气,病鸡伴以神经症状出现时,食欲减退或拒食的鸡只增多,病鸡下痢,发病后2~3天,鸡只死亡增加并与日剧增,大约在1周后死亡鸡数量开始下降。成年产蛋鸡发病,主要表现为呼吸困难和少数鸡只的神经症状,产蛋量明显下降,软壳蛋增多,并有少量鸡只死亡。&&&&&四、病理变化&&&&&典型新城疫的主要病变是全身黏膜和浆膜出血,淋巴系统肿胀、出血和坏死,尤其以消化道和呼吸道较为明显。嗉囊充满酸臭味的稀薄液体和气体。腺胃黏膜水肿,其乳头或乳头间有鲜明的出血点,或有溃疡和坏死,这是比较特征的病变。肌胃角质层下也常见有出血点。由小肠到盲肠和直肠黏膜有大小不等的出血点,肠黏膜上有纤维素性坏死性病变,有的形成假膜,假膜脱落后即成溃疡。盲肠扁桃体肿大、出血和坏死。气管充血或出血,肺有时可见瘀血或水肿。心冠脂肪有细小如针尖大的出血点。产蛋鸡的卵泡和输卵管显著充血,卵泡膜极易破裂以致卵黄流入腹腔引起卵黄性腹膜炎。&&&&&非典型新城疫病例大多可见到喉气管黏膜不同程度的充血、出血,输卵管充血、水肿;早期病例一般难发现消化道黏膜出血,在后期病死鸡中,如多剖检一些病例,有时可发现腺胃乳头和肌胃角膜下、十二指肠黏膜轻度出血。&&&&&五、诊断&&&&&根据流行特点、临床症状、病理变化和鉴别诊断,可对典型新城疫作出初步诊断,确诊及对非典型新城疫的诊断需借助于病毒的分离鉴定、血清学方法等实验室手段。&&&&&1.诊断要点&&&&&用抗生素类药物治疗无效或不能显著地控制病情;&&&&&鸡群出现呼吸困难,常有“咕噜”声,且排黄绿色粪便;&&&&&出现神经症状:转脖、站立不稳或卧地不起;&&&&&产蛋鸡群死淘率增高、产蛋数量减少、蛋壳质量下降,常出现软壳蛋、褪色蛋、畸形蛋等;&&&&&强毒感染或典型新城疫:腺胃乳头有出血点,小肠黏膜有枣核状紫红色出血、坏死灶;&&&&&血凝抑制(HI)试验,其结果显著升高或离散度增大。&&&&&2.鉴别诊断&&&&&鸡新城疫在发病初期症状不典型,主要表现为呼吸道症状,这样很容易与呼吸道传染病如低致病力流感、传染性支气管炎、传染性喉气管炎相混淆。有的呈现败血症,很容易与禽霍乱相混淆。&&&&&新城疫与低致病力流感(H9)&&&低致病力流感(H9)患鸡常有明显的流泪、肿眼、肿头,排白色稀粪。剖检时,消化道主要表现为腺胃乳头出血,十二指肠不规则斑点状出血,盲肠扁桃体出血,直肠及泄殖腔出血,上呼吸道有明显的炎症反应,肺脏因充血、炎症反应呈暗红色实变,产蛋鸡输卵管内炎性渗出物更为多见,肾脏一般可见变性肿胀或花斑肾病变。&&&&&新城疫与鸡传染性支气管炎&&传染性支气管炎传播速度快(1~2天可波及全群),一般只引起1~4周龄雏鸡的死亡,且无明显神经症状。另外传支还可引起肾脏病变,产蛋鸡产蛋率下降,产畸形蛋以及蛋清稀薄如水。&&&&&新城疫与传染性喉气管炎&&鸡传染性喉气管炎与新城疫都有气管内病变,但传染性喉气管炎无消化道病变。传染性喉气管炎多见于成年鸡,呼吸道症状更为严重,常见含血粘液咳出,眼结膜红肿,一般无明显的神经症状和黄绿色稀粪,剖检喉头及气管黏膜呈典型的出血性卡他性炎症或见黄白色干酪样坏死物。&&&&&新城疫与慢性呼吸道病&&&慢性呼吸道病病程长并易继发大肠杆菌感染而发生气囊炎、肝周炎、心包炎等,抗生素治疗效果显著。&&&&&&新城疫和禽霍乱&&禽霍乱多发生于成年鸡,常无症状而突然死亡,多发于季节交替时,病鸡肝脏表面具有特征性的灰白色坏死点及肝脏表面出血。抗生素治疗有效。&&&&&3.实验室诊断技术&&&&&目前所用的诊断技术包括常规诊断技术和分子诊断技术。常规诊断技术包括病毒的分离、血凝抑制试验(HI)、酶联免疫吸附试验(ELISA&)、琼脂扩散、鸡胚中和、蚀斑中和试验等血清学检测手段,其中血凝抑制试验(HI)因其操作简便快捷而在临床上应用最多。分子诊断技术包括单克隆抗体技术、核酸探针检测技术、基因体外扩增技术、限制性核酸内切酶分析等。&&&&&&六&、免疫防制&&&&&&1.免疫接种&&目前新城疫常用的疫苗大致可分为两类,即活疫苗和灭活苗。根据活疫苗所含病毒株的不同又可分为单价活苗和多价活苗。依据毒株毒力的强弱,单价活苗毒株可分成中等毒力、低毒力和无毒力三种。中等毒力:Mukteswar株(I系)因其毒力较强而仅适用于禽的加强免疫,一般用于60日龄以上的鸡;低毒力疫苗种类很多,主要有Lasota株、C1one30株、B1株(II系)、N79株等。无毒力的疫苗主要有V4株、VG/GA株、Ulster2C株等,疫苗对鸡不会诱发任何不良反应。特别是V4株疫苗由于具有耐热性和嗜肠道性,饮水免疫或拌料免疫效果优于其它弱毒疫苗等优点,而日益受到广泛关注。新城疫病毒多价苗主要有二价(含Lasota株和V4株)或三价活疫苗(含Lasota株、clone30株和V4株)&&&&&新城疫灭活疫苗多是用β-丙内酯或福尔马林灭活,而后加入氢氧化铝凝胶或油佐剂制成,选用的毒株一般。活疫苗既可以建立局部黏膜免疫(IgA),又可以刺激机体产生体液免疫和细胞免疫,但抗体水平相对较低,维持时间较短;油苗主要诱导机体产生体液免疫,其循环抗体水平比活苗高1~2个滴度,且维持时间长,抗体水平均匀一致。因此,将活疫苗与油苗结合免疫既可以建立良好的局部黏膜免疫,抵御新城疫病毒野毒从呼吸道和消化道入侵,又可以产生较高水平的循环抗体,消灭已经侵入机体的新城疫病毒野毒,二者结合,全方位将新城疫病毒野毒抵御在机体之外。&&&&&设计免疫程序时一定要考虑当地本病的疫情状况、饲养管理条件、疫苗毒株的特点、鸡群用途、鸡群免疫状况,并根据免疫检测的结果进行及时调整。建议免疫程序:蛋鸡5~8日龄Clone30点眼同时注射新城疫灭活疫苗,19~21日龄Lasota点眼,35&Lasota点眼,&60日龄肌注鸡新城疫中等毒力活疫苗(I系)同时注射新城疫灭活疫苗,110日龄肌注鸡新城疫中等毒力活疫苗(I系)同时注射新城疫、产蛋下降综合症二联灭活疫苗,&140日龄用Lasota点眼同时注射新城疫灭活疫苗。肉用仔鸡3~7日龄用Clone30滴鼻或点眼同时颈背部皮下注射新城疫灭活疫苗,20~23日龄Lasota滴鼻或点眼,30~33日龄Lasota饮水(可根据HI抗体监测情况具体确定是否进行第三次接种)。&&&&&2.做好鸡场(鸡舍)的空舍消毒、日常消毒工作&&尽量减少不同批次的鸡群在同舍或同场饲养,最好能做到全进全出。健全、完善鸡场的生物安全体系。&&&&&3.做好日常饲养管理&&注意保持鸡舍内温度、湿度,合理通风,给鸡群创造适宜的小环境,尽量减少应激。根据鸡的营养需求,提供优质全价的饲料,提高鸡群体质,增强鸡群抗病能&,用药以抗病毒11号和混感疫康配合使用&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&&
新闻录入:技术员:王立志 更新时间: 16:38:10
河北华强药业有限公司(技术研发部)&&&&鸡新城疫1系对仔猪腹泻的应用_百度知道
鸡新城疫1系对仔猪腹泻的应用
鸡新城疫1系对仔猪腹泻的应用
下痢,内含少量未消化食物。③成猪染病但绝大多数不发病、煎煮饮或灌服,按照每头2-4mg注射,大猪2~4天;5日龄内仔猪病死率95%~100%、肠毒清100斤/多数发病后2~7天死亡、发率可达100%。采用肠清 鞣酸蛋白 阿托品治疗仔猪传染性胃肠炎。1,仔猪为12~24小时。2,一日二次疗效极佳,粪便呈灰色或茶褐色。突然发病:在治疗方面,先注射阿托品本病的潜伏期随着猪日龄的不同而有很大差异。病程约5~7天。②肥育猪,病程短,食欲不振、首先;套,可减少死亡、煅龙骨,有恶臭。治疗方案。染,对体重无明显影响,腹泻初期有极少数猪呕吐,连用23天、肉桂。①哺乳仔猪,疗效越高。可用于猪群的预防和治疗,要早发现早治疗,如病情紧急(特殊)可点击我头像或名字。中药可选用地榆炭。满意请采纳,严重水样腹泻,水样腹泻,活性碳2-5g;严重病猪可后海穴封闭。患猪突然呕吐;下痢乳白色或黄绿色,同时口服次硝酸铋2-6g或鞣酸蛋白2-4mg、神曲,部分猪轻度腹泻或一时便软便,病毒性腹泻病,治疗越早,由于此病发病急,带有未消化的小块凝乳
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中国农业科学
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鸡传染性喉气管炎重组鸡痘病毒基因工程疫苗研究回顾与展望
王云峰,童光志
中国农业科学院哈尔滨兽医研究/所兽医生物技术国家重点实验室/禽传染病研究室,哈尔滨 150001
Review and Prospect of Bivalent Recombinant Vaccine Against Infectious Laryngotracheitis and Fowlpox
WANG Yun-feng, TONG Guang-zhi
Division of Avian Infectious Diseases/National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150001
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孙惠玲, 王云峰, 苗得园, 张培君, 智海东, 徐灵龙, 王 玫, 童光志, 汪 明. 表达鸡新城疫病毒F、HN基因和传染性喉气管炎病毒gB基因的重组鸡痘病毒的构建及其特性研究. 生物工程学报, 1-939.
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孙永科, 田占成, 王云峰, 童光志, 智海东, 刘胜旺, 王 玫, 杨增岐. 鸡传染性支气管炎病毒S1基因和鸡Ⅱ型干扰素基因在重组鸡痘病毒中的共表达. 畜牧兽医学报, ): 800-806.
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王云峰, 智海东, 王 玫, 仇华吉, 周艳君, 田志军, 张绍杰, 童光志. 表达传染性喉气管炎病毒gB基因重组鸡痘病毒疫苗的遗传稳定性评价. 中国预防兽医学报, ): 426-429.
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王云峰, 智海东, 王 玫, 孙永科, 仇华吉, 周艳君, 田志军, 张绍杰, 童光志. 抗鸡传染性喉气管炎重组鸡痘病毒基因工程疫苗同居感染试验. 中国预防兽医学报, ): 51-54.
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孙永科, 田占成, 王云峰, 刘胜旺, 童光志, 智海东, 王 玫. 表达鸡&-干扰素和传染性支气管病毒S1基因的重组鸡痘病毒疫苗对鸡外周血T淋巴细胞动态分布影响的研究. 中国预防兽医学报, ): 539-543.
王云峰, 智海东, 王 玫, 彭金美, 仇华吉, 周艳君, 田志军, 张绍杰, 童光志. 表达传染性喉气管炎病毒gB 基因重组鸡痘病毒疫苗免疫持续期试验. 中国预防兽医学报, ): 131-135.
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智海东, 王云峰, 童光志, 王 玫, 张绍杰. 传染性喉气管炎病毒gB基因和新城疫病毒F基因在重组禽痘病毒中共表达. 生物工程学报, ): 963-966.
石星明, 王云峰, 王 玫, 刘胜旺, 童光志, 徐灵龙, 贺 笋. 鸡传染性支气管重组鸡痘病毒基因工程疫苗对异源LHB 株病毒攻击的免疫保护. 广西农业生物科学, (Suppl.): 97-102.
Boyle D B, Coupar B E. Construction of recombinant fowlpox viruses as vector for poultry vaccines. Virus Gene, 3-356.
智海东, 王云峰, 孙永科, 杨玉艾, 王 玫, 童光志. 表达传染性喉气管炎病毒gB基因和新城疫病毒F基因重组鸡痘病毒疫苗免疫持续期试验. 中国预防兽医学报, ): 13-15.
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智海东, 王云峰, 张 晶, 王 玫, 王凤雪, 童光志. 传染性喉气管炎新城疫鸡痘重组病毒免疫效力的研究. 畜牧兽医学报, ): 807-811.
Taylor J, Weinberg R, Languet B, Desmettre P, Paoletti E. Recombinant fowlpox virus inducing protective immunity in non-avian species. Vaccine, ): 497-503.
孙惠玲, 王云峰, 苗得园, 张培君, 智海东, 徐灵龙, 王 玫, 童光志, 汪 明. 表达鸡新城疫病毒F、HN基因和传染性喉气管炎病毒gB基因的重组鸡痘病毒的构建及其特性研究. 生物工程学报, 1-939.
Webster R G, Kawaoka Y, Taylor J, Weinberg R, Paoletti E. Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens. Vaccine, ): 303-308.
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智海东, 王云峰, 孙永科, 张 晶, 王 玫, 彭金美, 刘永刚, 童光志. 表达传染性喉气管炎病毒gB基因和新城疫病毒F基因重组病毒免疫及强毒攻击后外周血T淋巴细胞亚群的动态. 中国预防兽医学报, ): 535-538.
孙永科, 田占成, 王云峰, 童光志, 智海东, 刘胜旺, 王 玫, 杨增岐. 鸡传染性支气管炎病毒S1基因和鸡Ⅱ型干扰素基因在重组鸡痘病毒中的共表达. 畜牧兽医学报, ): 800-806.
Tripathy D N, Schnitzlein W M. Expression of avian influenza virus hemagglutinin by recombinant fowlpox virus. Avian Diseases, 6-191.
Boyle D B, Heine H G. Influence of dose and route of inoculation on responses of chickens to recombinant fowlpox virus vaccines. Veterinary Microbiology, -2): 173-81.
张绍杰, 孟松树, 仇华吉, 王 柳, 倪键强, 何昭庆, 王 玫, 童光志. 鸡传染性喉气管炎病毒(ILTV)WG株糖蛋白gB基因序列比较分析. 中国兽医学报, ): 544-547.
智海东, 王云峰, 王 玫, 王利丽, 王凤雪, 张绍杰, 童光志. 新城疫病毒F基因与传染性喉气管炎病毒gB基因重组鸡痘病毒免疫保护产生时间的测定. 中国兽医科技, ): 41-44.
张绍杰, 童光志, 王 柳, 仇华吉, 倪建强, 孟松树, 于 力, 王 玫. 传染性喉气管炎病毒(ILTV)糖蛋白gB在重组鸡痘病毒中的表达. 中国预防兽医学报, ): 205-210.
Boyle D B, Coupar B E. Construction of recombinant fowlpox viruses as vector for poultry vaccines. Virus Gene, 3-356.
Webster R G, Taylor J, Pearson J, Rivera E, Paoletti E. Immunity to Mexican H5N2 avian influenza viruses induced by a fowl pox-H5 recombinant. Avian Diseases, 1-465.
孙永科, 田占成, 王云峰, 刘胜旺, 童光志, 智海东, 王 玫. 表达鸡&-干扰素和传染性支气管病毒S1基因的重组鸡痘病毒疫苗对鸡外周血T淋巴细胞动态分布影响的研究. 中国预防兽医学报, ): 539-543.
智海东, 王云峰, 孙永科, 杨玉艾, 王 玫, 童光志. 表达传染性喉气管炎病毒gB基因和新城疫病毒F基因重组鸡痘病毒疫苗免疫持续期试验. 中国预防兽医学报, ): 13-15.
Webster R G, Kawaoka Y, Taylor J, Weinberg R, Paoletti E. Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens. Vaccine, ): 303-308.
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孙惠玲, 王云峰, 苗得园, 张培君, 智海东, 徐灵龙, 王 玫, 童光志, 汪 明. 表达鸡新城疫病毒F、HN基因和传染性喉气管炎病毒gB基因的重组鸡痘病毒的构建及其特性研究. 生物工程学报, 1-939.
乔传玲, 于康震, 姜永萍, 张建林, 邓国华, 孟庆文, 田国斌, 唐秀英. 表达禽流感病毒核蛋白基因重组禽痘病毒的构建及其免疫保护性研究. 中国农业科学, 2003, (6): 705-708.
石星明, 王云峰, 王 玫, 刘胜旺, 童光志, 徐灵龙, 贺 笋. 鸡传染性支气管重组鸡痘病毒基因工程疫苗对异源LHB 株病毒攻击的免疫保护. 广西农业生物科学, (Suppl.): 97-102.
王云峰, 智海东, 王 玫, 仇华吉, 周艳君, 田志军, 张绍杰, 童光志. 表达传染性喉气管炎病毒gB基因重组鸡痘病毒疫苗的安全性试验与最小免疫剂量测定. 中国预防兽医学报, ): 441-444.
Boyle D B, Heine H G. Influence of dose and route of inoculation on responses of chickens to recombinant fowlpox virus vaccines. Veterinary Microbiology, -2): 173-81.
陈 平,陈素娟,彭大新,刘秀梵. 高效表达H9亚型禽流感病毒HA基因的重组鸡痘病毒的构建及免疫效力试验. 中国兽医学报, 6-218.
Taylor J, Weinberg R, Languet B, Desmettre P, Paoletti E. Recombinant fowlpox virus inducing protective immunity in non-avian species. Vaccine, ): 497-503.
孙永科, 田占成, 王云峰, 童光志, 智海东, 刘胜旺, 王 玫, 杨增岐. 鸡传染性支气管炎病毒S1基因和鸡Ⅱ型干扰素基因在重组鸡痘病毒中的共表达. 畜牧兽医学报, ): 800-806.
王云峰, 智海东, 王 玫, 仇华吉, 周艳君, 田志军, 张绍杰, 童光志. 表达传染性喉气管炎病毒gB基因重组鸡痘病毒疫苗的遗传稳定性评价. 中国预防兽医学报, ): 426-429.
Webster R G, Taylor J, Pearson J, Rivera E, Paoletti E. Immunity to Mexican H5N2 avian influenza viruses induced by a fowl pox-H5 recombinant. Avian Diseases, 1-465.
王云峰, 智海东, 王 玫, 孙永科, 仇华吉, 周艳君, 田志军, 张绍杰, 童光志. 抗鸡传染性喉气管炎重组鸡痘病毒基因工程疫苗同居感染试验. 中国预防兽医学报, ): 51-54.
孙永科, 田占成, 王云峰, 刘胜旺, 童光志, 智海东, 王 玫. 表达鸡&-干扰素和传染性支气管病毒S1基因的重组鸡痘病毒疫苗对鸡外周血T淋巴细胞动态分布影响的研究. 中国预防兽医学报, ): 539-543.
Tripathy D N, Schnitzlein W M. Expression of avian influenza virus hemagglutinin by recombinant fowlpox virus. Avian Diseases, 6-191.
Taylor J, Christensen L, Gettig R, Goebel J, Bouquet J F, Mickle T R, Paoletti E. Efficacy of a recombinant fowl pox-based Newcastle disease virus vaccine candidate against velogenic and respiratory challenge. Avian Diseases, 3-180.
乔传玲, 于康震, 姜永萍, 张建林, 邓国华, 孟庆文, 田国斌, 唐秀英. 表达禽流感病毒核蛋白基因重组禽痘病毒的构建及其免疫保护性研究. 中国农业科学, 2003, (6): 705-708.
陈 平,陈素娟,彭大新,刘秀梵. 高效表达H9亚型禽流感病毒HA基因的重组鸡痘病毒的构建及免疫效力试验. 中国兽医学报, 6-218.
Boyle D B, Coupar B E. Construction of recombinant fowlpox viruses as vector for poultry vaccines. Virus Gene, 3-356.
石星明, 王云峰, 王 玫, 刘胜旺, 童光志, 徐灵龙, 贺 笋. 鸡传染性支气管重组鸡痘病毒基因工程疫苗对异源LHB 株病毒攻击的免疫保护. 广西农业生物科学, (Suppl.): 97-102.
Taylor J, Edbauer C, Rey-Senelonge A, Bouquet J F, Norton E, Goebel S, Desmettre P, Paoletti E. Newcastle disease virus fusion protein expressed in a fowlpox virus recombinant confers protection in chickens. Journal of Virology, 41-1450.
王云峰, 智海东, 王 玫, 彭金美, 仇华吉, 周艳君, 田志军, 张绍杰, 童光志. 表达传染性喉气管炎病毒gB 基因重组鸡痘病毒疫苗免疫持续期试验. 中国预防兽医学报, ): 131-135.
Taylor J, Christensen L, Gettig R, Goebel J, Bouquet J F, Mickle T R, Paoletti E. Efficacy of a recombinant fowl pox-based Newcastle disease virus vaccine candidate against velogenic and respiratory challenge. Avian Diseases, 3-180.
Webster R G, Kawaoka Y, Taylor J, Weinberg R, Paoletti E. Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens. Vaccine, ): 303-308.
Taylor J, Weinberg R, Languet B, Desmettre P, Paoletti E. Recombinant fowlpox virus inducing protective immunity in non-avian species. Vaccine, ): 497-503.
Boursnell M E, Green P F, Samson A C, Campbell J I, Deuter A, Peters R W, Millar N S, Emmerson P T, Binns M M. A recombinant fowlpox virus expressing the hemagglutinin-neuraminidase of Newcastle disease virus protects chickens against challenge by NDV. Virology, : 297-300.
Boyle D B, Heine H G. Influence of dose and route of inoculation on responses of chickens to recombinant fowlpox virus vaccines. Veterinary Microbiology, -2): 173-81.
Taylor J, Edbauer C, Rey-Senelonge A, Bouquet J F, Norton E, Goebel S, Desmettre P, Paoletti E. Newcastle disease virus fusion protein expressed in a fowlpox virus recombinant confers protection in chickens. Journal of Virology, 41-1450.
Tripathy D N, Schnitzlein W M. Expression of avian influenza virus hemagglutinin by recombinant fowlpox virus. Avian Diseases, 6-191.
Boursnell M E, Green P F, Campbell J I, Deuter A, Peters R W, Tomley F M, Samson A C, Chambers P, Emmerson P T, Binns M M. Insertion of the fusion gene of Newcastle disease virus into a non-essential region in the terminal repeats of fowlpox virus and demonstration of protective immunity induced by the recombinant. Journal of General Virology, 1-628.
智海东, 王云峰, 童光志, 王 玫, 张绍杰. 传染性喉气管炎病毒gB基因和新城疫病毒F基因在重组禽痘病毒中共表达. 生物工程学报, ): 963-966.
智海东, 王云峰, 张 晶, 王 玫, 王凤雪, 童光志. 传染性喉气管炎新城疫鸡痘重组病毒免疫效力的研究. 畜牧兽医学报, ): 807-811.
Webster R G, Taylor J, Pearson J, Rivera E, Paoletti E. Immunity to Mexican H5N2 avian influenza viruses induced by a fowl pox-H5 recombinant. Avian Diseases, 1-465.
Ogawa R, Yanagida N, Saeki S, Saito S, Ohkawa S, Gotoh H, Kodama K, Kamogawa K, Sawaguchi K, Iritani Y. Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses. Vaccine, ): 486-490.
Boyle D B, Coupar B E. Construction of recombinant fowlpox viruses as vector for poultry vaccines. Virus Gene, 3-356.
Boursnell M E, Green P F, Samson A C, Campbell J I, Deuter A, Peters R W, Millar N S, Emmerson P T, Binns M M. A recombinant fowlpox virus expressing the hemagglutinin-neuraminidase of Newcastle disease virus protects chickens against challenge by NDV. Virology, : 297-300.
智海东, 王云峰, 孙永科, 张 晶, 王 玫, 彭金美, 刘永刚, 童光志. 表达传染性喉气管炎病毒gB基因和新城疫病毒F基因重组病毒免疫及强毒攻击后外周血T淋巴细胞亚群的动态. 中国预防兽医学报, ): 535-538.
乔传玲, 于康震, 姜永萍, 张建林, 邓国华, 孟庆文, 田国斌, 唐秀英. 表达禽流感病毒核蛋白基因重组禽痘病毒的构建及其免疫保护性研究. 中国农业科学, 2003, (6): 705-708.
Webster R G, Kawaoka Y, Taylor J, Weinberg R, Paoletti E. Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens. Vaccine, ): 303-308.
陈 平,陈素娟,彭大新,刘秀梵. 高效表达H9亚型禽流感病毒HA基因的重组鸡痘病毒的构建及免疫效力试验. 中国兽医学报, 6-218.
Letellier C, Burny A, Meulemans G. Construction of a pigeonpox virus recombinant: expression of the Newcastle disease virus (NDV) fusion glycoprotein and protection of chickens against NDV challenge. Archives of Virology, : 43-56.
Boursnell M E, Green P F, Campbell J I, Deuter A, Peters R W, Tomley F M, Samson A C, Chambers P, Emmerson P T, Binns M M. Insertion of the fusion gene of Newcastle disease virus into a non-essential region in the terminal repeats of fowlpox virus and demonstration of protective immunity induced by the recombinant. Journal of General Virology, 1-628.
智海东, 王云峰, 王 玫, 王利丽, 王凤雪, 张绍杰, 童光志. 新城疫病毒F基因与传染性喉气管炎病毒gB基因重组鸡痘病毒免疫保护产生时间的测定. 中国兽医科技, ): 41-44.
Boyle D B, Heine H G. Influence of dose and route of inoculation on responses of chickens to recombinant fowlpox virus vaccines. Veterinary Microbiology, -2): 173-81.
Nagy E, Robert J, Karell M. Vaccination of chickens with a recombinant fowlpox virus containing the Hemagglutinin- Neuraminidase gene of Newcastle Disease Virus under the control of the fowlpox virus Thymidine Kinase promoter. Canadian Journal of Veterinary Research, 6-308.
Taylor J, Christensen L, Gettig R, Goebel J, Bouquet J F, Mickle T R, Paoletti E. Efficacy of a recombinant fowl pox-based Newcastle disease virus vaccine candidate against velogenic and respiratory challenge. Avian Diseases, 3-180.
Ogawa R, Yanagida N, Saeki S, Saito S, Ohkawa S, Gotoh H, Kodama K, Kamogawa K, Sawaguchi K, Iritani Y. Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses. Vaccine, ): 486-490.
Webster R G, Taylor J, Pearson J, Rivera E, Paoletti E. Immunity to Mexican H5N2 avian influenza viruses induced by a fowl pox-H5 recombinant. Avian Diseases, 1-465.
智海东, 王云峰, 孙永科, 杨玉艾, 王 玫, 童光志. 表达传染性喉气管炎病毒gB基因和新城疫病毒F基因重组鸡痘病毒疫苗免疫持续期试验. 中国预防兽医学报, ): 13-15.
Taylor J, Edbauer C, Rey-Senelonge A, Bouquet J F, Norton E, Goebel S, Desmettre P, Paoletti E. Newcastle disease virus fusion protein expressed in a fowlpox virus recombinant confers protection in chickens. Journal of Virology, 41-1450.
Letellier C, Burny A, Meulemans G. Construction of a pigeonpox virus recombinant: expression of the Newcastle disease virus (NDV) fusion glycoprotein and protection of chickens against NDV challenge. Archives of Virology, : 43-56.
Iritani Y, Aoyama S, Takigami S, Hayashi Y, Ogawa R, Yanagida N, Saeki S, Kamogawa K. Antibody response to Newcastle disease virus (NDV) of recombinant fowlpox virus (FPV) expressing a Hemoaggltinin-neuraminidase of NDV into chickens in the presence of antibody to NDV or FPV. Avian Diseases, 9-661.
孙惠玲, 王云峰, 苗得园, 张培君, 智海东, 徐灵龙, 王 玫, 童光志, 汪 明. 表达鸡新城疫病毒F、HN基因和传染性喉气管炎病毒gB基因的重组鸡痘病毒的构建及其特性研究. 生物工程学报, 1-939.
孙永科, 田占成, 王云峰, 童光志, 智海东, 刘胜旺, 王 玫, 杨增岐. 鸡传染性支气管炎病毒S1基因和鸡Ⅱ型干扰素基因在重组鸡痘病毒中的共表达. 畜牧兽医学报, ): 800-806.
乔传玲, 于康震, 姜永萍, 张建林, 邓国华, 孟庆文, 田国斌, 唐秀英. 表达禽流感病毒核蛋白基因重组禽痘病毒的构建及其免疫保护性研究. 中国农业科学, 2003, (6): 705-708.
Nagy E, Robert J, Karell M. Vaccination of chickens with a recombinant fowlpox virus containing the Hemagglutinin- Neuraminidase gene of Newcastle Disease Virus under the control of the fowlpox virus Thymidine Kinase promoter. Canadian Journal of Veterinary Research, 6-308.
Boursnell M E, Green P F, Samson A C, Campbell J I, Deuter A, Peters R W, Millar N S, Emmerson P T, Binns M M. A recombinant fowlpox virus expressing the hemagglutinin-neuraminidase of Newcastle disease virus protects chickens against challenge by NDV. Virology, : 297-300.
Tomley F M, Mockett A P, Boursnell M E, Binns M M, Cook J K, Brown T D, Smith G L. Expression of the infectious bronchitis virus spike protein by recombinant vaccinia virus and induction of neutralizing antibodies in vaccinated mice. Journal of General Virology, ): .
陈 平,陈素娟,彭大新,刘秀梵. 高效表达H9亚型禽流感病毒HA基因的重组鸡痘病毒的构建及免疫效力试验. 中国兽医学报, 6-218.
孙永科, 田占成, 王云峰, 刘胜旺, 童光志, 智海东, 王 玫. 表达鸡&-干扰素和传染性支气管病毒S1基因的重组鸡痘病毒疫苗对鸡外周血T淋巴细胞动态分布影响的研究. 中国预防兽医学报, ): 539-543.
Iritani Y, Aoyama S, Takigami S, Hayashi Y, Ogawa R, Yanagida N, Saeki S, Kamogawa K. Antibody response to Newcastle disease virus (NDV) of recombinant fowlpox virus (FPV) expressing a Hemoaggltinin-neuraminidase of NDV into chickens in the presence of antibody to NDV or FPV. Avian Diseases, 9-661.
Boursnell M E, Green P F, Campbell J I, Deuter A, Peters R W, Tomley F M, Samson A C, Chambers P, Emmerson P T, Binns M M. Insertion of the fusion gene of Newcastle disease virus into a non-essential region in the terminal repeats of fowlpox virus and demonstration of protective immunity induced by the recombinant. Journal of General Virology, 1-628.
Taylor J, Christensen L, Gettig R, Goebel J, Bouquet J F, Mickle T R, Paoletti E. Efficacy of a recombinant fowl pox-based Newcastle disease virus vaccine candidate against velogenic and respiratory challenge. Avian Diseases, 3-180.
Wang X, Schnitzlein W M, Tripathy D N, Girshick T, Khan M I. Construction and immunogenicity studies of recombinant fowl poxvirus containing the S1 gene of Massachusetts 41 strain of infectious bronchitis virus. Avian Diseases, ): 831-838.
石星明, 王云峰, 王 玫, 刘胜旺, 童光志, 徐灵龙, 贺 笋. 鸡传染性支气管重组鸡痘病毒基因工程疫苗对异源LHB 株病毒攻击的免疫保护. 广西农业生物科学, (Suppl.): 97-102.
Tomley F M, Mockett A P, Boursnell M E, Binns M M, Cook J K, Brown T D, Smith G L. Expression of the infectious bronchitis virus spike protein by recombinant vaccinia virus and induction of neutralizing antibodies in vaccinated mice. Journal of General Virology, ): .
Ogawa R, Yanagida N, Saeki S, Saito S, Ohkawa S, Gotoh H, Kodama K, Kamogawa K, Sawaguchi K, Iritani Y. Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses. Vaccine, ): 486-490.
Taylor J, Edbauer C, Rey-Senelonge A, Bouquet J F, Norton E, Goebel S, Desmettre P, Paoletti E. Newcastle disease virus fusion protein expressed in a fowlpox virus recombinant confers protection in chickens. Journal of Virology, 41-1450.
Yu L, Liu W, Schnitzlein W M, Tripathy D N, Kwang J. Study of protection by recombinant fowl poxvirus expressing C-terminal nucleocapsid protein of infectious bronchitis virus against challenge. Avian Diseases, ): 340-348.
Taylor J, Weinberg R, Languet B, Desmettre P, Paoletti E. Recombinant fowlpox virus inducing protective immunity in non-avian species. Vaccine, ): 497-503.
Letellier C, Burny A, Meulemans G. Construction of a pigeonpox virus recombinant: expression of the Newcastle disease virus (NDV) fusion glycoprotein and protection of chickens against NDV challenge. Archives of Virology, : 43-56.
Wang X, Schnitzlein W M, Tripathy D N, Girshick T, Khan M I. Construction and immunogenicity studies of recombinant fowl poxvirus containing the S1 gene of Massachusetts 41 strain of infectious bronchitis virus. Avian Diseases, ): 831-838.
Boursnell M E, Green P F, Samson A C, Campbell J I, Deuter A, Peters R W, Millar N S, Emmerson P T, Binns M M. A recombinant fowlpox virus expressing the hemagglutinin-neuraminidase of Newcastle disease virus protects chickens against challenge by NDV. Virology, : 297-300.
Bayliss C D, Peters R W, Cook J K, Reece R L, Howes K, Binns M M, Boursnell M E. A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus. Archives of Virology, : 193-205.
Tripathy D N, Schnitzlein W M. Expression of avian influenza virus hemagglutinin by recombinant fowlpox virus. Avian Diseases, 6-191.
Nagy E, Robert J, Karell M. Vaccination of chickens with a recombinant fowlpox virus containing the Hemagglutinin- Neuraminidase gene of Newcastle Disease Virus under the control of the fowlpox virus Thymidine Kinase promoter. Canadian Journal of Veterinary Research, 6-308.
Boursnell M E, Green P F, Campbell J I, Deuter A, Peters R W, Tomley F M, Samson A C, Chambers P, Emmerson P T, Binns M M. Insertion of the fusion gene of Newcastle disease virus into a non-essential region in the terminal repeats of fowlpox virus and demonstration of protective immunity induced by the recombinant. Journal of General Virology, 1-628.
Yu L, Liu W, Schnitzlein W M, Tripathy D N, Kwang J. Study of protection by recombinant fowl poxvirus expressing C-terminal nucleocapsid protein of infectious bronchitis virus against challenge. Avian Diseases, ): 340-348.
Yanagida N, Ogawa R, Li Y, Lee L F, Nazerian K. Recombinant fowlpox viruses expressing the glycoprotein B homolog and the pp38 gene of Marek's disease virus. Journal of Virology, ): .
Boyle D B, Coupar B E. Construction of recombinant fowlpox viruses as vector for poultry vaccines. Virus Gene, 3-356.
Iritani Y, Aoyama S, Takigami S, Hayashi Y, Ogawa R, Yanagida N, Saeki S, Kamogawa K. Antibody response to Newcastle disease virus (NDV) of recombinant fowlpox virus (FPV) expressing a Hemoaggltinin-neuraminidase of NDV into chickens in the presence of antibody to NDV or FPV. Avian Diseases, 9-661.
Ogawa R, Yanagida N, Saeki S, Saito S, Ohkawa S, Gotoh H, Kodama K, Kamogawa K, Sawaguchi K, Iritani Y. Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses. Vaccine, ): 486-490.
Bayliss C D, Peters R W, Cook J K, Reece R L, Howes K, Binns M M, Boursnell M E. A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus. Archives of Virology, : 193-205.
Calvert J G, Nazerian K, Witter R L, Yanagida N. Fowlpox virus recombinant expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus induce neutralizing antibodies and reduce viremia in chickens. Journal of Virology, 69-3076.
Webster R G, Kawaoka Y, Taylor J, Weinberg R, Paoletti E. Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens. Vaccine, ): 303-308.
Tomley F M, Mockett A P, Boursnell M E, Binns M M, Cook J K, Brown T D, Smith G L. Expression of the infectious bronchitis virus spike protein by recombinant vaccinia virus and induction of neutralizing antibodies in vaccinated mice. Journal of General Virology, ): .
Letellier C, Burny A, Meulemans G. Construction of a pigeonpox virus recombinant: expression of the Newcastle disease virus (NDV) fusion glycoprotein and protection of chickens against NDV challenge. Archives of Virology, : 43-56.
Yanagida N, Ogawa R, Li Y, Lee L F, Nazerian K. Recombinant fowlpox viruses expressing the glycoprotein B homolog and the pp38 gene of Marek's disease virus. Journal of Virology, ): .
Boyle D B, Heine H G. Influence of dose and route of inoculation on responses of chickens to recombinant fowlpox virus vaccines. Veterinary Microbiology, -2): 173-81.
Nazerian K, Yanagida N. A recombinant fowlpox virus expressing the envelope antigen of subgroup a avian leukosis/Sarcoma virus. Avian Diseases, 4-520.
Wang X, Schnitzlein W M, Tripathy D N, Girshick T, Khan M I. Construction and immunogenicity studies of recombinant fowl poxvirus containing the S1 gene of Massachusetts 41 strain of infectious bronchitis virus. Avian Diseases, ): 831-838.
Nagy E, Robert J, Karell M. Vaccination of chickens with a recombinant fowlpox virus containing the Hemagglutinin- Neuraminidase gene of Newcastle Disease Virus under the control of the fowlpox virus Thymidine Kinase promoter. Canadian Journal of Veterinary Research, 6-308.
Cardona C J, Reed W M, Witter R L, Silva R F. Protection of turkeys from hemorrhagic enteritis with a recombinant fowl poxvirus expressing the native hexon of hemorrhagic enteritis virus. Avian Diseases, ): 234-244.
Webster R G, Taylor J, Pearson J, Rivera E, Paoletti E. Immunity to Mexican H5N2 avian influenza viruses induced by a fowl pox-H5 recombinant. Avian Diseases, 1-465.
Yu L, Liu W, Schnitzlein W M, Tripathy D N, Kwang J. Study of protection by recombinant fowl poxvirus expressing C-terminal nucleocapsid protein of infectious bronchitis virus against challenge. Avian Diseases, ): 340-348.
Iritani Y, Aoyama S, Takigami S, Hayashi Y, Ogawa R, Yanagida N, Saeki S, Kamogawa K. Antibody response to Newcastle disease virus (NDV) of recombinant fowlpox virus (FPV) expressing a Hemoaggltinin-neuraminidase of NDV into chickens in the presence of antibody to NDV or FPV. Avian Diseases, 9-661.
Calvert J G, Nazerian K, Witter R L, Yanagida N. Fowlpox virus recombinant expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus induce neutralizing antibodies and reduce viremia in chickens. Journal of Virology, 69-3076.
Swayne D E, Beck J R, Kinney N. Failure of a recombinant fowl poxvirus vaccine containing an avian influenza hemagglutinin gene to provide consistent protection against influenza in chickens preimmunized with a fowl pox vaccine. Avian Diseases, ): 132-137.
Tomley F M, Mockett A P, Boursnell M E, Binns M M, Cook J K, Brown T D, Smith G L. Expression of the infectious bronchitis virus spike protein by recombinant vaccinia virus and induction of neutralizing antibodies in vaccinated mice. Journal of General Virology, ): .
Bayliss C D, Peters R W, Cook J K, Reece R L, Howes K, Binns M M, Boursnell M E. A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus. Archives of Virology, : 193-205.
乔传玲, 于康震, 姜永萍, 张建林, 邓国华, 孟庆文, 田国斌, 唐秀英. 表达禽流感病毒核蛋白基因重组禽痘病毒的构建及其免疫保护性研究. 中国农业科学, 2003, (6): 705-708.
Nazerian K, Yanagida N. A recombinant fowlpox virus expressing the envelope antigen of subgroup a avian leukosis/Sarcoma virus. Avian Diseases, 4-520.
陈 平,陈素娟,彭大新,刘秀梵. 高效表达H9亚型禽流感病毒HA基因的重组鸡痘病毒的构建及免疫效力试验. 中国兽医学报, 6-218.
Yanagida N, Ogawa R, Li Y, Lee L F, Nazerian K. Recombinant fowlpox viruses expressing the glycoprotein B homolog and the pp38 gene of Marek's disease virus. Journal of Virology, ): .
Wang X, Schnitzlein W M, Tripathy D N, Girshick T, Khan M I. Construction and immunogenicity studies of recombinant fowl poxvirus containing the S1 gene of Massachusetts 41 strain of infectious bronchitis virus. Avian Diseases, ): 831-838.
Cardona C J, Reed W M, Witter R L, Silva R F. Protection of turkeys from hemorrhagic enteritis with a recombinant fowl poxvirus expressing the native hexon of hemorrhagic enteritis virus. Avian Diseases, ): 234-244.
Taylor J, Christensen L, Gettig R, Goebel J, Bouquet J F, Mickle T R, Paoletti E. Efficacy of a recombinant fowl pox-based Newcastle disease virus vaccine candidate against velogenic and respiratory challenge. Avian Diseases, 3-180.
Calvert J G, Nazerian K, Witter R L, Yanagida N. Fowlpox virus recombinant expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus induce neutralizing antibodies and reduce viremia in chickens. Journal of Virology, 69-3076.
Taylor J, Edbauer C, Rey-Senelonge A, Bouquet J F, Norton E, Goebel S, Desmettre P, Paoletti E. Newcastle disease virus fusion protein expressed in a fowlpox virus recombinant confers protection in chickens. Journal of Virology, 41-1450.
Yu L, Liu W, Schnitzlein W M, Tripathy D N, Kwang J. Study of protection by recombinant fowl poxvirus expressing C-terminal nucleocapsid protein of infectious bronchitis virus against challenge. Avian Diseases, ): 340-348.
Swayne D E, Beck J R, Kinney N. Failure of a recombinant fowl poxvirus vaccine containing an avian influenza hemagglutinin gene to provide consistent protection against influenza in chickens preimmunized with a fowl pox vaccine. Avian Diseases, ): 132-137.
Nazerian K, Yanagida N. A recombinant fowlpox virus expressing the envelope antigen of subgroup a avian leukosis/Sarcoma virus. Avian Diseases, 4-520.
Boursnell M E, Green P F, Samson A C, Campbell J I, Deuter A, Peters R W, Millar N S, Emmerson P T, Binns M M. A recombinant fowlpox virus expressing the hemagglutinin-neuraminidase of Newcastle disease virus protects chickens against challenge by NDV. Virology, : 297-300.
Bayliss C D, Peters R W, Cook J K, Reece R L, Howes K, Binns M M, Boursnell M E. A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus. Archives of Virology, : 193-205.
Cardona C J, Reed W M, Witter R L, Silva R F. Protection of turkeys from hemorrhagic enteritis with a recombinant fowl poxvirus expressing the native hexon of hemorrhagic enteritis virus. Avian Diseases, ): 234-244.
Yanagida N, Ogawa R, Li Y, Lee L F, Nazerian K. Recombinant fowlpox viruses expressing the glycoprotein B homolog and the pp38 gene of Marek's disease virus. Journal of Virology, ): .
Boursnell M E, Green P F, Campbell J I, Deuter A, Peters R W, Tomley F M, Samson A C, Chambers P, Emmerson P T, Binns M M. Insertion of the fusion gene of Newcastle disease virus into a non-essential region in the terminal repeats of fowlpox virus and demonstration of protective immunity induced by the recombinant. Journal of General Virology, 1-628.
Swayne D E, Beck J R, Kinney N. Failure of a recombinant fowl poxvirus vaccine containing an avian influenza hemagglutinin gene to provide consistent protection against influenza in chickens preimmunized with a fowl pox vaccine. Avian Diseases, ): 132-137.
Calvert J G, Nazerian K, Witter R L, Yanagida N. Fowlpox virus recombinant expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus induce neutralizing antibodies and reduce viremia in chickens. Journal of Virology, 69-3076.
Ogawa R, Yanagida N, Saeki S, Saito S, Ohkawa S, Gotoh H, Kodama K, Kamogawa K, Sawaguchi K, Iritani Y. Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses. Vaccine, ): 486-490.
Letellier C, Burny A, Meulemans G. Construction of a pigeonpox virus recombinant: expression of the Newcastle disease virus (NDV) fusion glycoprotein and protection of chickens against NDV challenge. Archives of Virology, : 43-56.
Nazerian K, Yanagida N. A recombinant fowlpox virus expressing the envelope antigen of subgroup a avian leukosis/Sarcoma virus. Avian Diseases, 4-520.
Cardona C J, Reed W M, Witter R L, Silva R F. Protection of turkeys from hemorrhagic enteritis with a recombinant fowl poxvirus expressing the native hexon of hemorrhagic enteritis virus. Avian Diseases, ): 234-244.
Nagy E, Robert J, Karell M. Vaccination of chickens with a recombinant fowlpox virus containing the Hemagglutinin- Neuraminidase gene of Newcastle Disease Virus under the control of the fowlpox virus Thymidine Kinase promoter. Canadian Journal of Veterinary Research, 6-308.
Swayne D E, Beck J R, Kinney N. Failure of a recombinant fowl poxvirus vaccine containing an avian influenza hemagglutinin gene to provide consistent protection against influenza in chickens preimmunized with a fowl pox vaccine. Avian Diseases, ): 132-137.
Iritani Y, Aoyama S, Takigami S, Hayashi Y, Ogawa R, Yanagida N, Saeki S, Kamogawa K. Antibody response to Newcastle disease virus (NDV) of recombinant fowlpox virus (FPV) expressing a Hemoaggltinin-neuraminidase of NDV into chickens in the presence of antibody to NDV or FPV. Avian Diseases, 9-661.
Tomley F M, Mockett A P, Boursnell M E, Binns M M, Cook J K, Brown T D, Smith G L. Expression of the infectious bronchitis virus spike protein by recombinant vaccinia virus and induction of neutralizing antibodies in vaccinated mice. Journal of General Virology, ): .
Wang X, Schnitzlein W M, Tripathy D N, Girshick T, Khan M I. Construction and immunogenicity studies of recombinant fowl poxvirus containing the S1 gene of Massachusetts 41 strain of infectious bronchitis virus. Avian Diseases, ): 831-838.
Yu L, Liu W, Schnitzlein W M, Tripathy D N, Kwang J. Study of protection by recombinant fowl poxvirus expressing C-terminal nucleocapsid protein of infectious bronchitis virus against challenge. Avian Diseases, ): 340-348.
Bayliss C D, Peters R W, Cook J K, Reece R L, Howes K, Binns M M, Boursnell M E. A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus. Archives of Virology, : 193-205.
Yanagida N, Ogawa R, Li Y, Lee L F, Nazerian K. Recombinant fowlpox viruses expressing the glycoprotein B homolog and the pp38 gene of Marek's disease virus. Journal of Virology, ): .
Calvert J G, Nazerian K, Witter R L, Yanagida N. Fowlpox virus recombinant expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus induce neutralizing antibodies and reduce viremia in chickens. Journal of Virology, 69-3076.
Nazerian K, Yanagida N. A recombinant fowlpox virus expressing the envelope antigen of subgroup a avian leukosis/Sarcoma virus. Avian Diseases, 4-520.
Cardona C J, Reed W M, Witter R L, Silva R F. Protection of turkeys from hemorrhagic enteritis with a recombinant fowl poxvirus expressing the native hexon of hemorrhagic enteritis virus. Avian Diseases, ): 234-244.
Swayne D E, Beck J R, Kinney N. Failure of a recombinant fowl poxvirus vaccine containing an avian influenza hemagglutinin gene to provide consistent protection against influenza in chickens preimmunized with a fowl pox vaccine. Avian Diseases, ): 132-137.
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