南京青少年性早熟医院 - 寻医问诊 - 健康养生
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南京青少年性早熟医院
　　南京青少年性早熟医院【上海鸿慈儿童医院】【24小时免费热线：】上海鸿慈儿童医院——广州胡亚美儿童医院是卫生部指定的全国儿童疑难杂症诊治指导中心之一。上海鸿慈儿童医院汇集知名儿科专家刘进行、张博佑等数十名权威儿科专家，他们临床经验丰富、医术精湛，以患者至上，一切以患者为出发点的信念，保证每一位患者都享受专家的治疗服务，帮助患病儿童重新拾回健康，帮助他们童年寻回色彩。
　　性早熟是怎么回事呢？它是怎么发生的呢？
　　性早熟的出现在目前来说是非常常见的。一般来说，女孩在8岁前发育或10岁前月经来潮、男孩在9岁前开始性发育，可诊断为性早熟。专家表示，与2005年前相比，近几年来，临床接诊的性早熟儿童病例越来越多，同时，儿童性早熟的年龄提前了2～3岁，小患者当中，女性占到90%以上。需要指出的是，“性早熟”儿童成人后患乳腺癌、宫颈癌、前列腺癌等性腺癌症的几率远远高于正常儿童。
　　除了化学问题，还有什么会导致孩子性早熟，是许多家长朋友们关心的问题。其实除了家长过早对儿童普及生理知识、接触成人用品外，食品中含有大量激素、添加剂，对儿童进补各种营养品以及流行快餐食品等，这些都易造成儿童“性早熟”。
　　影视的不良镜头、专家提醒，黄色、暴力的影视镜头可直接刺激儿童的大脑皮层活动，提前唤醒儿童的性意识。家长在平时的生活当中，要多留心孩子的改变，如果出现体重身高增长过快、乳房疼痛等情况，要及早到医院进行检查。
　　饮食的激素。此外，更要注意宝宝的喂养方式。儿童应在医生的指导下服用营养滋补剂，根据生理需要补充营养，不要盲目吃人参蜂王浆、西洋参等。现今市场上出售的家禽，不乏有用拌有快速生长剂的饲料喂养的，禽肉中的“促熟剂”残余主要集中在家禽头颈部分的腺体中，因此，鸡、鸭、鹅的颈部最好不要给孩子吃。冬季的草莓、葡萄、西瓜、西红柿等，春末提前上市的梨、苹果、橙和桃，几乎都是在“促熟剂”的帮助下才反季或提早成熟，一定要避免给幼儿食用。针对儿童市场的很多标榜“长高长壮”的补剂和口，服，液，相当部分含有激素成分。这些激素使孩子在五六岁时长得比同龄儿童高大壮实，其骨龄已达8岁或10岁。而等孩子进入正常发育阶段时，反而不见长了。
　　重视儿童性早熟，治疗性早熟健康新疗法
　　--“MOGT生物技术”让性早熟孩子恢复健康成长!
　　“MOGT生物技术”在美国儿童医学研究中心被成功研发，也离不开中国医学家的大力协助，其中，中国“胡亚美儿童医学研究院”中心数十位性早熟、矮小症专家参与了整个技术的研究，中国医学家在国内外最新研究理论的基础上对“MOGT生物技术”进行了更加科学的提升，使得“MOGT生物技术”更加适合中国儿童。
　　MOGT生物技术治疗性早熟，将基因分子及特殊药物定位序贯介入病灶，形成新的蛋白质结合的氨基酸序列，高度特异地识别和抑制GnRH脉冲分泌，使下丘脑促性腺激素释放激素(GnRH)脉冲发生器的脉冲频率与幅度恢复正常，降低性腺活动，平衡丘脑-垂体-性腺轴功能及内分泌调节功能，促使过于密集的神经毡及突触得以平衡。
　　由于“类似物释放技术(ART)可促使垂体释放与生长激素起协调作用的TSH，刺激GH因子活性，激活生长激素介质和IGF生长因子，靶向分裂软骨细胞，有效延迟骨骺闭合时间，促进蛋白质合成，增强对钠、钾、钙、磷、硫等重要元素的摄取与利用，促进人体新陈代谢，使躯体正常生长，其经络学及神经交叉学原理可平衡阴阳、提高免疫、排毒修复，在不影响儿童正常生长发育的前提下，对治疗性早熟、矮小症效果理想。
　　如果您想了解更多相关问题，可以随时点击网络在线咨询，或者直接拨打24小时免费专家热线：，上海鸿慈儿童医院专家将详细解答您的疑惑。
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　　【医院地址】上海市闸北区宝山路455号
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A 2011 report: The incidence of early
puberty in inland China, from ten years ago 0.5% has increased to
at present 5%, appearing a rapid growth trend.
“Bone age with greatest difference to
actual age was 3.8 years”, is similar to the age advancement
of early puberty girls, does this reveal the actual prevalence of
early mature boys is higher than determined only by judgment from
other aspects of sex characteristics? International authoritative
journal 2011 publish Chinese scholars study: For the first time
report gut flora participate the illness
course of precocious puberty. Shanghai Chinese traditional medicine
specialists early puberty prevention notes and Chinese traditional
medicine prescription. EU considers that feeding-bottles
containing recocious puberty, from March 1, 2011
forbid production of feeding-bottles containing BPA.
To blindly increase milk production,
some farms will use hormones drugs to the cows.
gut flora, or might
or similar effect substance, for the
health of children, at home as well as at school, should keep away
from such kinds of “food”!
Why Does Precocious
Translated & Edited by Chen
Technology & Mankind Safety”
researcher
Chinese Specialists: Three major harms of early puberty to
girls: [1]
20041%“”100.5%1.3%1311[6]
report in 2004: China early puberty average incidence was 1%;
Guangzhou's children "precocious puberty" rates was 0.5% 10 years
ago which has now increased to 1.3%; Guangzhou children commonly
enter the age of adolescence when they reach 11 years old, compared
with the original average 13 [6]
2004(1),,(2),[7]
study published in 2004: “Conclusion: (1) Girls with precocious puberty, bone
development accelerates, matures in advance, and illness is more
serious and accelerate with the more serious degree of puberty
advance. (2) Traditional Chinese medicine has obvious slowing
effect on children skeleton growth, and delays bone mature
development.” [7]
2011330669020%3.8
China Football Association in 2011 examined bone age of
3306 youth players: Bone age of 690 players accounting about 20%
exceeded their actual age, maximum exceeding 3.8 years of
33066906903.8
The football association has held a national youth league bid and
bone age testing conferences, according to the latest data, among
the 3306 players accepting the bone age test, those of which bone
age exceeds actual age players accounted to 690 people. Tang Feng,
vice minister of competition of the football association, said
yesterday, most of the 690 players experiences earlier body
development, with only a few false age cases. According to the bone
age examination data, the bone age with greatest difference to
actual age was 3.8 years.
Advisor Chen
comments: “Bone age with greatest difference to
actual age was 3.8 years”, is similar to the age advancement
of early puberty girls, does this reveal the actual prevalence of
early mature boys is higher than determined only by judgment from
other aspects of sex characteristics? Does this reveal that should
also consider advance extent of bone age as one of the important
criterions for determining early mature boys? Is the mechanism and
course of advance bone age for early mature boys the same as the
mechanism and course of advance puberty of
In survey of 23,000 children (kindergarten to the primary school
grade three), task group found 84 cases of precocious puberty, the
male 9 cases, female 75 cases. Result: Zhejiang coastal area
children precocious puberty incidence to 0.38%.
Investigation shows, town early puberty rate was 0.45%, higher than
the 0.32% of the rural areas. The economic developed area incidence
0.50%, higher than 0.32% of the le areas along
highways and factory pollution area incidence 0.52% compared with
less pollution areas& 0.28%, respectively.
This shows that precocious puberty is influenced by environmental
factors, and influenced by mother early menarche, take nourishing
medicine and diet and so on.
A epidemiology investigation jointly carried out by the Children
& Youth Health Staff Room, Public Health College of
Shanghai Fudan University, and Pediatric Hospital of Fudan
University shows, the prevalence of early puberty in Shanghai is
&around 1%,
ranking the second illness only to obesity, accounting for the
second pediatric endocrine diseases. The investigation is China's
first precocious puberty survey statistics: from over 30,000
respondents, incidence is 1%, which is rather close to overseas
reported precocious puberty average rates 0.7% -
20099.23012.53.3
A 2009 Survey: Chinese girl’s mean puberty age on average is 9.2 years,
3.3 years earlier than 12.5 years 30 years ago
20099.23012.53.3
In 2009, the Pediatrics Endocrinology & Genetic
Metabolism Branch of Chinese Medical Society published a survey
showed that Chinese girl’s mean puberty age on average is 9.2
years, 3.3 years earlier than 12.5 years 30 years
effect of hormone-like contaminants in the environment, intake of
food or medicine containing sex hormones, are the main reasons
promoting early adolescence.
2010 Chongqing Pediatric Hospital Report [13]
199030199830020041000200020%
Prof. Lei Pei-yun
studied children early puberty and treatment for a long time at the
Pediatric Hospital. Prof. Lei confirmed, when the
Endocrinology Dept. Early Puberty Clinic was established in 1990,
every year it only received around 30 patients with early puberty,
but received 300 such patients by 1998. By 2004, this increased to
over 1000 patients. During recent years, they received about 2000
patients each year. Calculation accordingly, the incidence of early
puberty increases at a rate over 20% each year.
International authoritative journal
2011 publish Chinese scholars study: For the first time
report gut flora participate the illness
course of precocious puberty [14]
Prof. Zhang Yongyu, Jia Wei, Chinese Traditional Medicine
Prescription Examination & Systems Biology Research
Center of Shanghai University of Traditional Chinese Medicine,
jointly with science research members of the Children’s
Hospital affiliated to Shanghai Jiaotong
University, found obvious difference metabolic patterns between
precocious puberty girls to normal girls, the former tend to have
heavier bodies, and through further study found that the course of
precocious puberty disease is directly related to alteration
of three major perturbed metabolic pathways,
catecholamine, serotonin metabolism and tricarboxylic acid
6prolactinluteotropic hormone,
LHfollicle-stimulating hormone,
FSHEstradiol, E20.71.51.611.5
The study identified 6 kinds of hormones related to development of
precocious puberty disease, especially prolactin, luteotropic
hormone (LH), follicle-stimulating hormone (FSH) and estradiol
(E2increases 0.7, 1.5, 1.6 and 11.5
respectively compared to
healthy control groups. The
study was also the first to report that an alteration in symbiotic
gut microbial (gut flora)
composition is involved in the development of CPP
(Central Precocious Puberty)
condition, and the application prospect of
metabonomics in disease diagnosis method, these results of the
research analyzed potential targets for precocious puberty
treatment by traditional Chinese medicine.
“085”20111025Molecular and Cellular
Proteomics[15]
This study was supported by the National Nature Science Foundation
and the Shanghai Education Committee “085” subject connotation
construction supporting fund. The study was published on Oct. 25,
2011 by the international authoritative journal “Molecular and
Cellular Proteomics”, and received strong attention and appraise
within the concerned academic field. [15]
Shanghai Chinese traditional medicine
specialists early puberty prevention notes and Chinese traditional
medicine prescription [16]
Regarding treatment of precocious puberty with Chinese traditional
medicine, specialists consider the clinical
symptom of precocious puberty is “syndrome of hyperactivity of fire due to
deficiency of kidney Yin”, propose treatment principle of “Moist
kidney Yin, effuse hyperactivity of fire”, propose a prescription
based on Shengdi, Zhimu, Huangbo etc. have rather ideal
Regarding daily diets, Prof. Zhang Yong-yu,
Shanghai University of Traditional
Chinese Medicine, and others suggest, should eat less necks of
poultry, silkworm pupae, chicken embryo etc., eat less against
season vegetables, Western fast-food, eat less
Healthcare products, like animal foremilk, royal jelly, protein
powder, all kinds of “grow high, grow strong” oral administration
liquids, and avoid healthcare supplementary Chinese medicine,
like Chinese caterpillar fungus, Ginseng,
Longan, Flower powder, Toad oil etc.
Should also pay special attention to environment pollution,
like detergent agents, pesticides, plastic
products and excessive sunshine etc.
Zhengzhou pediatrics specialist: Avoid not
appropriate food causing precocious puberty
Is precocious puberty generated by
But much precocious puberty are generated by "eating". According to
Liu Jin-quan, Director, Children Healthcare Center of
Zhengzhou Pediatric Hospital,
many food contain hormones,
especially fried foods such as fried chicken wings, fried potato
chips and other Western fast food favored in the market, are likely
to cause the child adipose accumulation and abnormal early
development.
Mei-zhen, vice director, pediatrics dept. of Zhejiang People's
hospital, explained, eating large amounts of soy products causes
child precocious puberty, mainly is because soybean and its
products contains soybean isoflavone, a kind of plant estrogen. The
chemical composition of isoflavone is very similar to estrogen,
which can act as a estrogen substitute to promote bone cell
According to the special function of the soybean products, doctors
at first applied it in the treatment of osteoporosis of menopausal
women. Due to ovarian function decline of menopausal women, body
estrogen stimulation to osteoblast is
significantly reduced, easy to cause osteoporosis. Research found
that soybean isoflavone can be used by post-menopausal women as an
estrogen substitute to prevent osteoporosis. Therefore, doctors
will encourage in menopausal women eat more soybean
However, the plant estrogen of soybean products acts like a double
edged sword, has certain benefits to adults, but for children is
like a dose of the "catalyst": if children eat a lot of soybean
products, the plant estrogen would disrupt the normal growth and
development of the child, with the most direct consequences being
precocious puberty, which if not found in time, and if timely
intervention is not adopted, could advance the child’s bone age,
cause early healing of bone age
which is one of the main reasons for short
stature. Therefore experts remind, it is necessary not to
continuously eat a lot of soybean products for a long period of
time before full development of children, according to the child's
actual situation doctors will propose specific how much soybean
products are appropriate.
A201131ABPA[19]
EU considers that feeding-bottles
containing bisphenol A (or BPA for short) induce precocious puberty, from March 1, 2011
forbid production of feeding-bottles containing BPA.
Some time ago, EU considers that when heated BPA could separate out
into food and drinks, might disrupt metabolic process of humans, have negative
effect on infant development and immunity, and even cause cancer.
EU has from March 1 forbid production of feeding bottles containing
BPA, and from June forbid import of any feeding bottles containing
BPA into members of EU.
Specialists says there is possibility
of source of milk containing estrogens [20]
The shadow of Melamine has not been completely cleared, media
starts reporting about suspects that a brand of baby milk powder
might cause precocious puberty and breast development of infants.
The Ministry of Health on August 10, 2010 responded that they can
not conclude connection between the precocious baby and particular
food or the environment. The reporter interviewed concerned expert
who expressed their opinions to concerned issues.
Wang Shuhuai, Researchers, China Veterinary Drug Monitoring
Jinghua Times: The
Ministry of Health spokesman said powdered milk does not allow
detection of estrogen, but you in the conference stated that "the
rules set the standard limit of detection", excuse me, is milk
powder allowed or not allowed to contain
&Wang Shuhuai: The
spokesman said milk powder is not permitted detect synthetic
estrogen material add to the product. The estrogen I mentioned
refers to natural estrogen hormones existing within the cow’s body,
these hormones also exist within human body. This includes two
types of hormone, the follicle-stimulating hormone and promote
progestin. If milk powder contains these two types of hormones, and
their content level conforms to international organization
standards, this is allowed by the Ministry of Agriculture, is a
normal phenomenon.
Zongyi, Committee member, Children Health Special Committee to
China Medical Doctor Association
Jinghua Times: In which
link of milk powder manufacturing is more likely occur the problem
of adding hormone or hormone residues?
Ding Zongyi: It is not necessary to add hormones during the milk
powder process, because it won't improve the taste, will not
increase the production, will not reduce cost, and instead
significantly increase cost of production. From the perspective of
no benefit, no motivation, it is not possible. But, in cases of sick cows, and to
blindly increase milk production, some farms will use antibiotics
and hormones drugs. Therefore, can not eliminate such problems
exist at milk cow farms.
参考文献：
References:
[2] Jennifer Ashton, Puberty starting earlier for many
girls: study, CBS News, April 12, 2011
广州孩子青春期提前二年　性早熟发病率也较高，信息时报，
Guangzhou children enter puberty two years earlier, early puberty
incidence is also rather high, Information Times,
[7] at el.，中国中西医结合杂志
，2004年11期
Bin at el., Girls precocious puberty abnormal skeletal development
law and treatment effect by traditional Chinese medicine which
moisture Yin and purges heat within the body, Combine Traditional
Chinese and Western Medicine Journal, 2004(11)
[8] 足协称多数骨龄超标青少年球员系身体发育较早，
Yong-jun, China Football Association claimed that most youth
players with exceeding bone age are due to body early development,
Jinghua Times,
Beijing Sports University, China Football Association national
youth football league bone age examination results is announced,
Li-peng, Zhejiang coastline area precocious puberty survey, girls 7.3 times
compared with boys, Hangzhou website & City Express,
近年我国儿童性早熟发病状况，医学教育网，
Recent year China’s children precocious
puberty situation, Medical Education Website,
姬少亭，新华调查：“性早熟”时代，我们怎样教育孩子？，新华网，
Xu Xiao-qing, Ji Shao-ting, Xinhua Survey:
“Neoteny”era, how should we educate children?,
Xinhua website,
Poor food causes rapid increase in children early puberty, 60% are
girls, Chongqing Evening News,
金恒，我国内地女童性早熟发病率上升至5%，新民晚报，
Jin Heng, China’s inland girls early puberty prevalence increased
to 5%, Xinmin Evening News,
et al., Urinary metabolite markers of precocious
puberty, Molecular and Cellular
Proteomics, Epub 2011 Oct 25.
[16] 20111130
Xu Ruizhe, Treatment of early puberty, Shanghai specialist
prescription, Jiefang Daily,
precocious puberty generated by food?,
Oriental Todays Daily,
Eat to much soybean processed food, 6 years old girl reaches
puberty early, Zhejiang On-line Health Website,
BPA plastic feeding-bottles induce precocious pubertyEU from today forbids, supermarket in
China are still selling, Xinjingbao Daily,
京华时报，专家会诊女婴性早熟原因
暂不能断定与奶粉有关，
Jinghua Times, Experts consultation on causes of baby girls
precocious puberty, at present can't judge if related or not with
the milk powder,
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